Recent advances in genetics and brain biochemistry point to the Abeta peptide as the major culprit in causing neurodegeneration in Alzheimer’s Disease (AD). This book summarizes current knowledge of the Abeta peptide and its role in AD. Written by specialists in this fast moving area, the book covers fundamental biochemical studies on this peptide, the genetic impact on Abeta expression and processing, and various AD therapeutic strategies that target Abeta.
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Abeta Peptide and Alzheimer’s Disease summarizes current knowledge of beta-amyloid peptide (Aß) and its role as the major culprit in Alzheimer’s Disease (AD), shown by recent advances in genetics and brain biochemistry.
Written by leaders in the industrial and academic world specializing in this rapidly moving area, the book covers fundamental biochemical studies on the Aß peptide, the genetic impact on Aß expression and processing, and various AD therapeutic strategies that target Aß. Although specifically focusing on Aß and AD, there is also some discussion on the similarity and differences of this peptide and AD with other amyloidogenic diseases, such as prion disease, Parkinson’s and Huntington’s.
This book will primarily be of interest to AD researchers and clinicians but also to researchers of other amyloid diseases.
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copper coordination, septal cultured neurons, antyloid plaques, cortical molecular layer, antyloid precursor protein, tau transgenic mice, tau mice, tau filament formation, plaque clearance, neurotibrillary tangles, mutant tau, neuritic dystrophy, pathological cascade, tau filaments, tau aggregates, amyloid burden, tau pathology, tau gene mutation, human tau, tau phosphorylation, precursor protein processing, plaque pathology, senile plaque cores, diffuse plaques, amyloid protein precursor Key Phrases - Capitalized Phrases (CAPs): (learn more)
Biol Chem, Proc Natl Acad Sci, Neurohiol Aging, Ann Neurol, Nat Med, Neurosci Lett, Brain Res, Arch Neurol, Neurobiol Aging, Acta Neuropathol, Neurosci Res, Neuropathol Exp Neurol, Nat Genet, Biochem Biophys Res Commun, Trends Neurosci, Neurohiol Dis, Biol Client, Cell Biol, Ncurohiol Aging, Neurobiol Dis, Neurol Sci, Mol Neurosci, Neural Transco, Free Radic Biol Med, Brain Pathol New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
copper coordination, septal cultured neurons, antyloid plaques, cortical molecular layer, antyloid precursor protein, tau transgenic mice, tau mice, tau filament formation, plaque clearance, neurotibrillary tangles, mutant tau, neuritic dystrophy, pathological cascade, tau filaments, tau aggregates, amyloid burden, tau pathology, tau gene mutation, human tau, tau phosphorylation, precursor protein processing, plaque pathology, senile plaque cores, diffuse plaques, amyloid protein precursor Key Phrases - Capitalized Phrases (CAPs): (learn more)
Biol Chem, Proc Natl Acad Sci, Neurohiol Aging, Ann Neurol, Nat Med, Neurosci Lett, Brain Res, Arch Neurol, Neurobiol Aging, Acta Neuropathol, Neurosci Res, Neuropathol Exp Neurol, Nat Genet, Biochem Biophys Res Commun, Trends Neurosci, Neurohiol Dis, Biol Client, Cell Biol, Ncurohiol Aging, Neurobiol Dis, Neurol Sci, Mol Neurosci, Neural Transco, Free Radic Biol Med, Brain Pathol New!
Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
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