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Acid-base balance has earned a reputation as a difficult subject to understand. This should not be the case. Presented in a logical fashion, with proper attention paid to the basic physiologic and chemical principles involved, acid-base balance should in fact be quite easy to master. This book attempts to "demystify" the subject, an understanding of which is a necessity for those who practice in the critical care setting.
The text is divided into three sections. Section I deals with the basic chemistry and physiology of acid-base balance. Clinical acid-base disturbances are discussed in Section II. Finally, the relationship between acid-base homeostasis and electrolyte balance is described in Section III.
The emphasis in Section I is on buffer systems--what they are and how they work. The dynamic nature of equilibrium systems and their relationship to buffers is also discussed. Pulmonary and renal control of plasma carbon dioxide and bicarbonate is explained. An understanding of topics discussed in Section I provides a foundation for mastery of the material in Section II, the clinical acid-base disturbances.
Four basic derangements of acid-base balance are discussed in Section II (metabolic and respiratory acidosis and alkalosis). Illustrations are used to clarify the underlying processes responsible for each condition. The synergistic action of the kidney and lung in the repair of acid-base disturbances is stressed.
Electrolyte disturbances associated with acid-base derangement are discussed in Section III. Here the focus is on primary and secondary deficiencies in potassium and chloride, usually seen in metabolic alkalosis.
This text focuses on the "basic science" of acid-base homeostasis, the chemistry and physiology involved in maintaining a stable plasma hydrogen ion concentration. As such, it cannot, and indeed should not, serve as a definitive guide for treatment of clinical acid-base and electrolyte disturbances. Many excellent texts are available for this purpose. It is hoped, however, that an understanding of the material presented here will provide those who care for patients suffering acid-base disturbances with a clearer focus on the subject, resulting in more effective treatment.
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Most Helpful Customer Reviews
3 of 3 people found the following review helpful:
5.0 out of 5 stars
About time to understand acid-base!,
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This review is from: Acid-Base Balance (Spiral-bound)
Acid-base balance has long been considered a very difficult subjectto understand but it is an every day task for health care professionals who must evaluate acid-base balance and electrolyte imbalance in their patients. I really liked this book because it explains how acids and bases interact in the kidney, lung and total body in an easy to understand, quantitative and pictorial fashion, without complicated equations and calculations. This book would be very useful for anyone involved in health care. It explains the metabolic pathways that maintain normal electrolyte balance and what happens to cause electrolyte imbalance when these processes are altered. It gives some examples of how electrolyte disturbances occur in conditions such as prolonged diarrhea or diabetes mellitus. By making it easier to understand the factors that produce electrolyte disturbance, this book helps the reader understand how to treat or prevent acid-base imbalance. As an author of a detailed textbook on renal physiology, I think the unique aspect of this book is that the material is presented in an easy to understand way while also providing complete explanations along with written, graphic and pictorial examples. This book provides a thorough overview of acid- base balance. As a physiologist and someone who taught acid-base physiology for over 35 years to all levels of students including medical students, nursing students and allied health students, I think anyone involved in any aspect of health care would find this book helpful to enhance their understanding of acid-base balance and electrolyte disturbances in the body. I highly recommend this book for anyone involved in health care. By: Esmail Koushanpour, Ph.D. Emeritus Professor, Northwestern University Medical School
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