Acute toxicology testing constitutes the first line of defense against potentially dangerous chemicals. This book provides a detailed presentation of protocols for each of the common designs, reviews their development and objectives, discusses the types of data they generate, and examines the current status of alternative test designs and models. For each test, applicable U.S. and international guidelines are also presented, and the formulation and selection of vehicles, dosages, and test animals are addressed.
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Inside This Book
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First Sentence:
Acute toxicity studies, as defined in this book, are those which evaluate the short-term (less than 30 days) adverse biological effects of a single exposure (or a small number of exposures over a week or less) to a material. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
first challenge application, second challenge application, acute systemic toxicity studies, appropriate skin site, cervicodorsal subcutis, control group guinea pigs, filter paper patch, primary dermal irritation index, primary dermal irritation study, lethality testing, test group animals, spaced dosages, acute toxicology testing, contact photosensitization, minimum lethal dosage, lethality curve, small animal clipper, rabbit eye irritation tests, mouse ear swelling test, acute inhalation study, lethality data, moving average interpolation, nonirritating concentration, wide elastic bandage, eye irritation testing Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Mary Ann Liebert, Academic Press, Hemisphere Publishing, United States, Marcel Dekker, Acclimatization Period, John Wiley, Raven Press, Acta Pharmacol, Black Light, Cambridge University Press, Ocular Toxicol, Post-Treatment Group, Telford Press, Buehler Assay, Churchill Livingstone, Consumer Product Safety Commission, Hill Top Chamber, British Toxicology Society, Department of Transportation, Invest Dermatol, New Concepts, Rabbit Screening Procedure, Study Procedure New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Acute toxicity studies, as defined in this book, are those which evaluate the short-term (less than 30 days) adverse biological effects of a single exposure (or a small number of exposures over a week or less) to a material. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
first challenge application, second challenge application, acute systemic toxicity studies, appropriate skin site, cervicodorsal subcutis, control group guinea pigs, filter paper patch, primary dermal irritation index, primary dermal irritation study, lethality testing, test group animals, spaced dosages, acute toxicology testing, contact photosensitization, minimum lethal dosage, lethality curve, small animal clipper, rabbit eye irritation tests, mouse ear swelling test, acute inhalation study, lethality data, moving average interpolation, nonirritating concentration, wide elastic bandage, eye irritation testing Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Mary Ann Liebert, Academic Press, Hemisphere Publishing, United States, Marcel Dekker, Acclimatization Period, John Wiley, Raven Press, Acta Pharmacol, Black Light, Cambridge University Press, Ocular Toxicol, Post-Treatment Group, Telford Press, Buehler Assay, Churchill Livingstone, Consumer Product Safety Commission, Hill Top Chamber, British Toxicology Society, Department of Transportation, Invest Dermatol, New Concepts, Rabbit Screening Procedure, Study Procedure New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 65
books:
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14
books
cite this book:
See all 14 books citing this book
- In Vitro Toxicology: New Directions (Alternative Methods in Toxicology Series) by Alan M. Goldberg on 6 pages
- Safety Evaluation: International Regulations for Drug and Medical Device Approval by Shayne C. Gad on 5 pages
- Principles and Methods of Toxicology by A Wallace Hayes on 5 pages
- Statistics and Experimental Design for Toxicologists, Third Edition by Shayne C. Gad on 4 pages
- Acute Toxicity Testing: Alternative Approaches (Alternative Methods in Toxicology Series) by Alan M. Goldberg on page 77, page 180, and page 237
See all 65 books this book cites
- Acute Toxicology Testing, Second Edition by Shayne C. Gad in Front Matter, and page 49
- Riot Control Agents: Issues in Toxicology, Safety & Health by Eugene J. Olajos on page 114
- Using the Pharmaceutical Literature (BOOKS IN LIBRARY AND INFORMATION SCIENCE) by Sharon Srodin on page 71
- Clinical Toxicology: Principles and Mechanisms by Frank A. Barile on page 85
- Handbook of Pre-Clinical Continuous Intravenous Infusion by Guy Healing on page 160
See all 14 books citing this book
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