Adhesion Molecules in Hematology (Acta Haematologica) [Hardcover]

E. Cacciola (Author)

Book Description

ISBN-10: 3805563930 | ISBN-13: 978-3805563932 | Publication Date: August 1996

Effective hematopoiesis occurs through a series of steps involving proliferation, development and differentiation of early haematopoietic progenitor cells and ultimately leads to the release of mature cells into the peripheral blood. This process is dependent on discrete cell-cell and cell-matrix interactions which are regulated by expression of adhesion molecules. This publication highlights the critical role played by adhesion molecules in both normal and pathological hematopoiesis. Several reviews focus on the regulation and expression of haematological malignancies, which is likely to play an important part in the anatomical distribution and progression of the disease. Further topics include homing and trafficking of haemopoietic progenitor cells, adhesive interactions in haemostasis, as well as the roles of adhesion in cancer spread and in graft-versus-host-disease. Writen by experienced investigators, this compilation of reviews provides an excellent overview of the latest advances in the field and will be essential reading for haematologists, oncologists, intemists, pathologists, cell and molecular biologists.

Product Details

• Hardcover: 126 pages
• Publisher: S Karger Pub (August 1996)
• Language: English
• ISBN-10: 3805563930
• ISBN-13: 978-3805563932
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