This volume represents an up-to-date survey of current (mainly clinical) research on the treatment of primary breast cancer, summarizing most of the expert lectures given at the 4th International Conference on Adjuvant Therapy of Primary Breast Cancer in February 1992 in St. Gallen, Switzerland. It covers relevant topics from biological mechanisms on cell kill and overcoming drug resistance to new aspects of breast conserving surgery and adjuvant endocrine as well as cytotoxic therapies; updating results of most important international trials on adjuvant therapy of breast cancer. Of particular importance is a closing summary reporting the common opinions of an `international consensus' on risk-adapted adjuvant therapy of breast cancer, setting the stage for optimal treatment of breast cancer patients both clinically and psycho-socially. The volume is a 'must' for all clinicians and scientists in the field of breast cancer.
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