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Adrenoceptors: Structure, Function and Pharmacology
 
 
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Adrenoceptors: Structure, Function and Pharmacology [Hardcover]

Robert Ruffolo (Author)

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Book Description

June 1, 1995 3718656442 978-3718656448 1
Its comprehensive scope and contribution from experts in their respective fields makes this book a novel and unique contribution to the field of adrenoceptor research.
Research into the field of adrenoceptors has undergone explosive growth during the past decade, with the elucidation of the molecular structures of the three major families of adrenoceptors, namely the small alpha, Greek1, small alpha, Greek2 and ß adrenoceptors, and of their functions within the confines of the cellular membrane. Rational systems and schemes for the subclassification and nomenclature of the adrenoceptors have been devised and it has been demonstrated that multiple subtypes exist for each of the major adrenoceptor families. The role of adrenoceptors in homeostasis and disease is discussed.

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Inside This Book (learn more)
First Sentence:
It has been nearly a century since the discovery that adrenal extracts, when injected into animals, would mimic many of the physiological effects of sympathetic nerve stimulation (Lewandowsky, 1898; Langley, 1901), and that ergot alkaloids would block some, but not all, of these effects (Dale, 1906). Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
adrenoceptor research, adenylylcyclase activation, functional subclassification, rat proximal colon, rat parotid gland, cloned subtypes, rat submaxillary gland, spleen membranes, atypical receptor, affinity estimates, dog carotid artery, various target cells, prazosin binding, neonatal rat lung, hypnotic response, low affinity form, rat soleus muscle, canine saphenous, guinea pig atrium, rabbit thoracic aorta, competition binding assays, functional selectivity, rat thoracic aorta, catecholamine binding, receptive sites
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Biol Chem, British Journal of Pharmacology, Molecular Pharmacology, Life Sci, Mol Pharmacol, Beecham Pharmaceuticals, King of Prussia, Pharmacological Sciences, European Journal of Pharmacology, Journal of Biological Chemistry, Swedeland Road, Circulation Research, National Institutes of Health, Trends Pharmacol, Acad Sci, Biochemical Pharmacology, Departments of Pharmacology, Naunyn-Schmiedeberg's Archives of Pharmacology, Palo Alto, Pharmacol Exp, Burl Chem, Creighton University School of Medicine, Exp Ther, New York, Proc Natl
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