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Adrenomedullin in Cardiovascular Disease (Basic Science for the Cardiologist)
 
 
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Adrenomedullin in Cardiovascular Disease (Basic Science for the Cardiologist) [Hardcover]

Toshio Nishikimi (Editor)

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Book Description

April 28, 2005 0387254048 978-0387254043 1

Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease.


Editorial Reviews

From the Back Cover

Adrenomedullin was discovered in 1993 in an extract of human pheochromocytoma while monitoring cAMP levels in rat platelets. Adrenomedullin has attracted considerable interest among cardiologists due to its impact on the cardiovascular system which includes a decrease in blood pressure in vivo; an impact on vascular smooth muscle cells; increases cAMP levels; indirectly reduces blood pressure and has a role in the pathogenesis of arteriosclerosis.

Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease.

Toshio Nishikimi, MD, PhD, is an Associate Professor in the Department of Hypertension and Cardiorenal Medicine, Dokkyo University School of Medicine, Tochigi, Japan.

About the Author

Toshio Nishikimi, MD, PhD, is an Associate Professor in the Department of Hypertension and Cardiorenal Medicine, Dokkyo University School of Medicine, Tochigi, Japan.


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Inside This Book (learn more)
First Sentence:
In 1993, we discovered adrenomedullin (AM) in human pheochromocytoma tissue by monitoring the ability of the cell extracts to increase intracellular cyclic AMP (cAMP) levels in rat platelets. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
adrenomedullin expression, human adrenomedullin gene, adrenomedullin production, adrenomedullin gene expression, adrenomedullin infusion, plasma adrenomedullin, novel hypotensive peptide, circulating adrenomedullin, pheochromocytoma tissue, adrenomedullin levels, adrenomedullin concentrations, adrenomedullin receptors, secrete adrenomedullin, immunoreactive adrenomedullin, adrenal zona glomerulosa cells, adrenomedullin stimulates, rat endothelial cells, regulation profile, human pheochromocytoma, paracrine inhibitor, myocardial apoptosis, vasodilatory peptide, mean pulmonary arterial pressure, beneficial hemodynamic, various cardiovascular diseases
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Biochem Biophys Res Commun, Biol Chem, Hypertens Res, Regul Pept, Life Sci, Clin Endocrinol Metab, Clin Sci, Clin Invest, Kidney Int, Cardiovasc Res, Circ Res, Clin Exp Pharmacol Physiol, Crit Care Med, Microsc Res Tech, Mol Endocrinol, Endocr Rev, Physiol Heart Circ Physiol, Arterioscler Thromb Vase Biol, C-terminal Tyr, Cire Res, Mol Med, Proc Natl Acad Sci
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