This book is meant for specialists in digestive diseases with a particular interest in the management of inflammatory bowel disease and for specialists who are seeking opinions about new or controversial methods of treatment. Nonspecialists should also consult this book, however, because many of the topics are of general interest to gastroenterologists and internists. It could also be useful for medical students and trainees in gastroenterology or internal medicine.
The 11 sections of the book cover all treatments for inflammatory bowel disease, not only in adults but also in children. There are chapters on patient-physician interactions and, for pediatric patients, family-physician interactions. The authors stress that the patient should be the primary manager of his or her chronic disease and should be guided and coached by a physician to find the best therapeutic regimen. Collaboration between physicians and surgeons is also stressed as a guarantee of better care for patients. An example of such collaboration is the typical management of severe ulcerative colitis. The support services for patients described in the book (e.g., nurse advocates for patients with inflammatory bowel disease, the Crohn's and Colitis Foundation of America, and consultation about nutrition) are of great interest. Indeed, the chapter by Rood on lifestyle issues is remarkable, and I recommend reading it first.
The section on diagnostic methods is detailed; the contribution of transabdominal bowel sonography to clinical decision making is important, since this noninvasive method is valuable for diagnosis, for the detection of complications, and for follow-up in patients with inflammatory bowel disease. An example of a computer data base for patients with inflammatory bowel disease is given. Such a data-base system is indispensable, both at the individual level (the gastroenterologist) and the collective level (the referral center), and can facilitate progress in epidemiology, pathophysiology, and pharmacoeconomics. The digestive and extradigestive complications of inflammatory bowel disease are well covered, and the importance of the location of Crohn's disease (i.e., gastroduodenal, jejunoileal, or perianal) is analyzed.
The various classes of medical treatment for ulcerative colitis and Crohn's disease are also covered in detail. Sequential and combined therapy is emphasized, with special attention to the location and intensity of the disease, its responsiveness to steroids, the ratio of efficiency to side effects, the management of acute flares, and maintenance therapy.
Enteral and parenteral nutrition as alternatives to chemical treatment, especially in Crohn's disease, is discussed. The sections on the surgical management of ulcerative colitis and Crohn's disease describe procedures (particularly laparoscopically assisted bowel resection), long-term results, and support for patients who undergo ostomy and pouch surgery. Behavioral therapy, stress and pain management, and alternative methods of care (whose use is often motivated by patients' dissatisfaction) are also mentioned.
One may regret the absence of a chapter on future therapeutic approaches, such as gene therapy, or the fact that some topics (e.g., aminosalicylates, corticosteroids, immunomodulators, and anticytokines) are covered in more than one chapter, but these are minor criticisms of a book that is a vast source of information on the treatment of patients with inflammatory bowel disease.
Bruno L. Bonaz, M.D., Ph.D.
Copyright © 2001 Massachusetts Medical Society. All rights reserved. The New England Journal of Medicine is a registered trademark of the MMS.
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This review is from: Advanced Therapy of Inflammatory Bowel Disease (Hardcover)
I was diagnosed with Crohn's Disease in 1990. I have had three bowel resections with a fourth probable for this year. I have suffered moderate to severe Crohn's with numerous complications that required medical intervention. I am the type of patient that seeks out all the information available. I found this book at Ochsner Clinic Foundation Hospital's medical library. It covers every possible topic associated with the cause, treatment and research involved with IBD written by the top people in this field. I will purchase this book as a valuable resource for my personal library and to assist me in working with my GI doctor on treatment for my Crohn's. I highly recommend this for anyone involved with IBD's who want to know as much as possible about this illness.
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