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The purpose of this article is to review the mechanism of T-cell lineage commitment in the thymus.
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Key Phrases - Statistically Improbable Phrases (SIPs):
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separate lineage model, rearrangement model, double negative cells, central tolerance induction, lineage decision, mycobacterial phagosome, including hematopoiesis, lineage cells, cell receptor transgenic mice, human fas ligand, cell antigen receptor genes, human dendritic cells, lineage commitment, phagosome maturation, murine listeriosis, productive rearrangements, junctional sequences, rearrangement status, thymic cellularity, adult thymus, intracellular bacteria, thymocyte development, thymic deletion, nontransgenic mice, fetal thymocytes
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Cancer Res, Nature Med, Cell Biol, Academic Press, Genes Dev, Lees Miller, Cancer Inst, Daudi Burkitt, Davis Smith, Department of Immunology, New York, Van Kaer, Van Parijs
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