This volume presents a collection of invited papers from the First European Workshop on Molecular Toxicology, held in Sophia Antipolis, France. It covers eight selected topics in molecular toxicology. The first two are devoted to "physics", dealing respectively with advanced instrumentation enabling location and quantification of xenobiotics in cells and organs, and computer-assisted assessment of risk (QSAR). A comprehensive and up-to-date survey of molecular toxicology in the pharmaceutical industry is included. The third section addresses the effect of xenobiotics on cell-cycle actors. Sections 4-6 deal with molecular toxicology in skin, kidney, nerve, liver and pancreatic cells. The last two sections describe methods to probe DNA damage and repair, and immunotoxicity.
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