First Sentence:
Huntington's Disease (HD) is an autosomal dominant neurodegenerative disorder characterized by progressive cognitive deficits, psychiatric disturbances and involuntary choreiform movements, typically beginning in mid-adulthood and progressing towards death approximately 18 years from onset (Hayden, 1981; Harper, 1991; Leavitt et al., 1999).
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Key Phrases - Statistically Improbable Phrases (SIPs):
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general cell death pathway, human basal ganglia reconsidered, hemiparkinsonism rats, huntingtin cleavage, autoantibody mediated demyelination, parkin protein, cleave huntingtin, parkinsonism mice, expanded polyglutamine stretches, transfected neurons, human huntingtin, parkin gene, nigrostriatal denervation, basal ganglia organization, smn gene, apoptotic stress, caspase cleavage sites, huntingtin fragments, cytoprotective properties, rat brain microsomes, striatal cells, juvenile parkinsonism, repeat instability, spinocerebellar ataxia type, pathogenic gene
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Ann Neurol, Nat Genet, Neurosci Lett, Hum Mol Genet, Biol Chem, Proc Natl Acad Sci, Exp Neurol, Brain Res, Mov Disord, Neurol Sci, Neural Transm, Nature Genet, Biochem Biophys Res Commun, Ben Shachar, Hum Genet, Japan Summary, Brain Pathol, Cell Biol, Department of Pharmacology, Federal Republic of Germany, Ministry of Education, Acta Neuropathol, Hum Gene Ther, Nat Med, Neurobiol Aging
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