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It Ain't Necessarily So: The Dream of the Human Genome and Other Illusions
 
 
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It Ain't Necessarily So: The Dream of the Human Genome and Other Illusions [Paperback]

Richard Lewontin (Author)
3.9 out of 5 stars  See all reviews (11 customer reviews)

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Book Description

September 30, 2001
Is our nature—as individuals, as a species—determined by our evolution and encoded in our genes? If we unravel the protein sequences of our DNA, will we gain the power to cure all of our physiological and psychological afflictions and even to solve the problems of our society? Today biologists—especially geneticists—are proposing answers to questions that have long been asked by philosophy or faith or the social sciences. Their work carries the weight of scientific authority and attracts widespread public attention, but it is often based on what the renowned evolutionary biologist Richard Lewontin identifies as a highly reductive misconception: "the pervasive error that confuses the genetic state of an organism with its total physical and psychic nature as a human being."

In these nine essays covering the history of modern biology from Darwin to Dolly the sheep, all of which were originally published in The New York Review of Books, Lewontin combines sharp criticisms of overreaching scientific claims with lucid expositions of the exact state of current scientific knowledge—not only what we do know, but what we don't and maybe won't anytime soon. Among the subjects he discusses are heredity and natural selection, evolutionary psychology and altruism, nineteenth-century naturalist novels, sex surveys, cloning, and the Human Genome Project. In each case he casts an ever-vigilant and deflationary eye on the temptation to look to biology for explanations of everything we want to know about our physical, mental, and social lives.

These essays—several of them updated with epilogues that take account of scientific developments since they were first written—are an indispensable guide to the most controversial issues in the life sciences today.

The second edition of this collection includes new essays on genetically modified food and the completion of the Human Genome Project. It is an indispensable guide to the most controversial issues in the life sciences today.

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Editorial Reviews

Amazon.com Review

Stephen Jay Gould calls Richard Lewontin "simply the smartest man I have ever met." And not the least opinionated, either. Lewontin has long been famous among biologists for a volatile combination of feisty leftism, scientific insight, and verbal skill, which have been displayed for the more general public in his essays for what has been called The New York Review of Each Other's Books.

It Ain't Necessarily So is a collection of some of his more characteristic reviews from the 1980s and 1990s. The Mismeasure of Man, by Stephen Jay Gould; Unto Others: The Evolution and Psychology of Unselfish Behavior, by Elliott Sober and David Sloan Wilson; sociological studies of Sex in America; and Ruth Hubbard's books on gender in science: all his essays are informative yet lively, with a high acid content--as when he begins his piece on the Human Genome Project with a definition of "fetish."

Lewontin's prose is worth reading in itself, but what lifts this anthology to another level is that it also includes replies and rebuttals selected from the New York Review's letters column--a forum that doubles as the intellectual's World Wrestling Federation. For the older pieces, he also includes updates, "where are they now" summaries to give a sense of historical change in each field. Assertive, brilliant, sarcastic, dense, wide-ranging--Lewontin may be challenging, but he is never dull. --Mary Ellen Curtin --This text refers to the Hardcover edition.

From Publishers Weekly

Harvard biologist Lewontin is highly skeptical of the human genome project supporters' claims that complete knowledge of the human organism and effective gene therapies are just around the corner. His forceful critique of this multimillion-dollar gene-mapping project points out that our DNA is infinitely complex, and that mutations in genes are not the cause of, say, cancer, although they may be one of many predisposing conditions. In a bracing, lucid collection of essays, all originally published in the New York Review of Books, Lewontin makes bold forays into such fields as evolutionary theory, IQ testing, criminology, artificial intelligence, neurobiology and gender differences, exposing sloppy thinking and fallacies on all fronts. Scrutinizing "the development of modern biology from Darwin to Dolly" (a reference to the sheep cloned in 1997), Lewontin lambastes Clinton's National Bioethics Advisory Commission, charging that its report on the possibility of human cloning sidestepped fundamental ethical, religious and political issues. Lewontin is a formidable critic of simplistic, flawed biological determinism, which he sees at work in studies of identical twins reared apart; in feminist biologists' claim that females are the smarter, gentler, more humane sex; in sociobiologist E.O. Wilson's belief that the sexual division of power flows directly from innate differences between men and women; and in biologist Richard Dawkins's argument for the primacy of genes over the social environment. Several of these rigorous essays include an exchange of letters between Lewontin and his critics, making this an illuminating forum of ideas. (May)
Copyright 2000 Reed Business Information, Inc. --This text refers to the Hardcover edition.

Product Details

  • Paperback: 368 pages
  • Publisher: New York Review Books (September 30, 2001)
  • Language: English
  • ISBN-10: 0940322951
  • ISBN-13: 978-0940322950
  • Product Dimensions: 5.1 x 1 x 7.5 inches
  • Shipping Weight: 13.1 ounces (View shipping rates and policies)
  • Average Customer Review: 3.9 out of 5 stars  See all reviews (11 customer reviews)
  • Amazon Best Sellers Rank: #641,809 in Books (See Top 100 in Books)

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Customer Reviews

11 Reviews
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29 of 40 people found the following review helpful:
4.0 out of 5 stars Maybe it is, January 13, 2001
This book is a collection of nine essays from The New York Review of Books, beginning in 1981, mostly on genetics, the genome and the Darwinian pantheon. The essays are presented with new footnotes and cross references followed by an Exchange and/or an Epilogue in which the material is updated and some contrary points of view presented and addressed. The expression is erudite, polished and complex, the tone authoritative and at times slyly satirical and not more than a microbe's breath away from the pompous.

The first essay, "The Inferiority Complex" is a review of Stephen Jay Gould's The Mismeasure of Man (1981) which deals with the IQ conundrum. Lewontin's main point here, in agreement with Gould, is that "there may be genes for the shape of our heads, [but] there cannot be any for the shape of our ideas" (p. 9). I'm not sure I agree with that rousing call to the uniqueness of human kind, but I am confident that no one has yet refuted such a point of view. Not entirely as a surprise Gould (in a jacket blurb) acknowledges Lewontin as "the smartest man I have ever met."

Gould is not the only one to sing praises to Lewontin's intellect and understanding. Noam Chomsky chimes in with an acknowledgment of "the impressive quality and significance" of Lewontin's essays, while a book I just finished reading, Steve Jones's excellent Darwin's Ghost (1999) is dedicated to Lewontin, who showed him "what evolution can and cannot explain." Perhaps that is Lewontin's main strength, as a anchor on the ship of biological presumption that would sail us to a questionable nirvana of the pre-determined. I can say from my own experience that the very learned professor reminds me of someone I would call "the Edmund Wilson of book critics biological." He is also the very distinguished Alexander Agassiz Research Professor at Harvard and the author of several books on genetics and related subjects, most characteristically perhaps, Not in Our Genes (1984) with Steven P. R. Rose and Leon J. Kamin.

Why then am I not entirely thrilled with this beautifully wrought collection of unquestionably significant and stimulating essays? I think it's that I disagree with his point of view and emphasis, and feel that the sequencing of the human genome really is a significant step toward our understanding of who and what we are, and I don't care who, or who did not, get rich in advancing it.. I also think that the practical applications from such information may prove valuable in ways we cannot begin to predict. I am a fool for knowledge if only for knowledge's sake, and I wonder why Lewontin has expended so much energy knocking the project. His real criticism of the effort, despite his use of the derogatory words, "dream" and "illusion" and even "fetish" (p. 135) is presented on page 177: "The promise of great advances in medicine, not to speak of our knowledge of what it is to be human, is yet to be realized from sequencing the human genome."

Who could disagree with that? He also writes on page 151, "Causal stories are lacking...nor is it clear, when actual cases are considered, how therapies will flow from a knowledge of DNA sequences." Again, who could disagree? However this is political-speak. It says nothing that can be seized upon and found derogatory, yet hints at failure and disappointment. Characteristically, Lewontin writes nothing that one can find direct fault with, yet by indirection and association he belittles the effort. I would note that the word "fetish" is not used directly as a coloration of the project, but as an indirect association. People have said that The New York Review of Books is really The New York Review of Each Others Books, and therefore constitutes a close-knit club with a shared political point of view. I will withhold such a judgment since I have only a passing familiarity with that very prestigious publication.

Putting all that aside, I found myself, while reading the third chapter, "Darwin, Mendel, and the Mind," wondering if Lewontin was really conscious of his own thought processes when on page 103 he relates that he "passed among three very different mental states all under the control of the willful I." Ah, if only that "willful I" really was in control and had the power to consciously regulate our mental states. Lewontin seems unaware that it takes many years of devoted practice to still the "monkey mind" and allow one an observation of one's mental processes. He asks rhetorically (still on p. 103), the question he calls the "central problem...for neurobiology," namely, "What is "I"? This is indeed a profound question, asked at least as early as the Upanishads. The modern answer, which Lowentin must know, but does not present, is that the I is an illusion that we cannot help but believe. He goes on to argue with Daniel Dennett against the idea of consciousness as a "metaphorical delusion" (p. 105) without realizing that there is a crucial difference between a "delusion," metaphorical or otherwise, and an illusion. If he looks more closely he might find that consciousness is a trick of the evolutionary process, the main purpose of which is to make us fear death by forcing us to identify intensely with our particular phenotype. Our subjective appreciation of consciousness is a wondrous byproduct of that identification.

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3 of 3 people found the following review helpful:
4.0 out of 5 stars Interesting contrarian ideas, if you can take the hubris, March 22, 2009
This review is from: It Ain't Necessarily So: The Dream of the Human Genome and Other Illusions (Paperback)
Other reviews have touched on the content of the essays in detail. I'll just say the following:

PROS:
- The topics are generally quite interesting, and Lewontin's comments are at times eye-opening, casting serious doubt on established doctrine.
- He writes very well (although he seems to be showing off a bit with vocabulary and the use of French).

CONS:
- He seems quite opinionated. I find his words compelling enough to be more suspicious of what others have said, but at times I don't really feel that I can trust his opinion. There are many examples of this, one being that he is thoroughly convinced of the validity of group selection and can't understand why everyone else doesn't see it. It's all so clear to him...
- At times he seems to delight in being nasty, in choosing hurtful ways to say things, as though that were part of his responsibility in reviewing the work of others.

Occasionally I found the book almost painful to read. For some of the essays, in which he tried to lay waste to the egos of others, he includes their responses as well -- so that he can take one last swipe at them. I actually did skip a few pages in the middle of the book, where he was taking one of these last swipes -- I couldn't stand it. I wanted to shout "Richard, go to your room!"

Still, the book is a thought-provoker, worth reading. Just be forewarned that the author gets a D-minus on "Plays well with others."
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10 of 14 people found the following review helpful:
5.0 out of 5 stars A Wonderful Collection of Essays, March 18, 2001
By 
Bradley P. Rich (Salt Lake City, UT USA) - See all my reviews
(REAL NAME)   
First a word on the format of this book: This is a collection of Lewontin's articles written for The New York Review of Books of the last decade. In each case Lewontin has chosen a topic of general interest in the general area of the biological sciences and written a survey of the area intended for the general reader. In typical New York Review fashion, this survey is done in the guise of a review of one or more books recently published in the area.

The columns are much more survey than book review and serve as excellent introductions to the disciplines for the non-specialist reader. Lewontin has included wonderful ascerbic responses to his columns and has updated the area with an epologue to each chapter that surveys recent developments.

The topics will interest the general reader: Recent Darwinian thinking, intelligence testing and brain metrics, the genome project, the biology of sexual equality, biology of the mind and cloning. In every case, Lewontin surveys the intellectual terrain and provides insight. In excellant survey of biological developments for the general reader.

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Inside This Book (learn more)
First Sentence:
THE FIRST MEETING of Oliver Twist and young Jack Dawkins, the Artful Dodger, on the road to London was a confrontation between two stereotypes of nineteenth-century literature. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
gene myth, bioethics commission
Key Phrases - Capitalized Phrases (CAPs): (learn more)
The New York Review, United States, Ruth Hubbard, The Mismeasure of Man, Richard Lewontin, The Code of Codes, National Research Council, National Academy of Sciences, Charles Darwin, Jacques Loeb, The Social Organization of Sexuality, National Academy Press, Oxford University Press, The New York Times, The Politics of Women's Biology, Walter Gilbert, Basic Books, Cyril Burt, Exploding the Gene Myth, Gregor Mendel, Jean-Pierre Changeux, Professor Ruse, Richard Dawkins, Stolen Harvest, University of California
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