Asthma is a disease of high prevalence that has shown a trend toward increasing incidence, morbidity, and mortality over the last three decades despite apparently effective drug treatments and increasing awareness of the need for better disease management. Often the inflammatory component of asthma is studied; however, the tissue remodelling process is a significant process that should not be overlooked. This valuable reference synthesizes current data and concepts developed to determine the relationship between airway wall remodelling and the pathogenesis of asthma. It discusses evidence for structural changes in asthmatic airway, the relationship between airway thickening and hyperresponsiveness, the relationship between cytokine production and tissue remodelling and inflammation, the significance of epithelial changes and the extracellular matrix, and in vivo and in vitro experimental approaches to the assessment of remodelling. Pharmacological and biochemical mechanisms that control cell proliferation are also examined. The consequences of airway wall remodelling for airway hyperresponsiveness is the unique focus of this volume, offering a fresh perspective of advances in asthma research.
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Patients with asthma report symptoms of variable wheeze, chest tightness, shortness of breath, cough, and sputum production. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
airway smooth muscle growth, canine tracheal smooth muscle cells, rabbit airway smooth muscle cells, nonasthmatic cases, cultured airway smooth muscle cells, nonfatal asthma, airway wall remodelling, human airway smooth muscle cells, excessive airway narrowing, smooth muscle shortening, airway smooth muscle proliferation, smooth muscle shortens, maximal airway narrowing, bovine tracheal myocytes, airway wall thickness, inner wall area, outer wall area, bronchial smooth muscle cells, membranous bronchioles, bronchial segments, airway dimensions, atopic asthmatic subjects, cartilaginous airways, contractile agonists, cell proliferation induced Key Phrases - Capitalized Phrases (CAPs): (learn more)
Cell Mol, Cell Biol, Respir Dis, Rev Respir, Allergy Clin, Care Med, New York, Academic Press, Marcel Dekker, Cell Res, Lung Cell, Cell Mot, Lung Res, Acad Sci, Genes Dev, Encyclopedia of Immunology, Proc Natl, Agents Actions, Allergy Appl, Ant Rev, Cell Mal, Allergy Chn, Ani Rev, Exp Med, Leukocyte Biol New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Patients with asthma report symptoms of variable wheeze, chest tightness, shortness of breath, cough, and sputum production. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
airway smooth muscle growth, canine tracheal smooth muscle cells, rabbit airway smooth muscle cells, nonasthmatic cases, cultured airway smooth muscle cells, nonfatal asthma, airway wall remodelling, human airway smooth muscle cells, excessive airway narrowing, smooth muscle shortening, airway smooth muscle proliferation, smooth muscle shortens, maximal airway narrowing, bovine tracheal myocytes, airway wall thickness, inner wall area, outer wall area, bronchial smooth muscle cells, membranous bronchioles, bronchial segments, airway dimensions, atopic asthmatic subjects, cartilaginous airways, contractile agonists, cell proliferation induced Key Phrases - Capitalized Phrases (CAPs): (learn more)
Cell Mol, Cell Biol, Respir Dis, Rev Respir, Allergy Clin, Care Med, New York, Academic Press, Marcel Dekker, Cell Res, Lung Cell, Cell Mot, Lung Res, Acad Sci, Genes Dev, Encyclopedia of Immunology, Proc Natl, Agents Actions, Allergy Appl, Ant Rev, Cell Mal, Allergy Chn, Ani Rev, Exp Med, Leukocyte Biol New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 43
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14
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- Cytokines of the Lung (Lung Biology in Health and Disease) by J. Kelley on 5 pages
- Encyclopedia of Immunology, Four-Volume Set, Second Edition by Ivan M. Roitt on 5 pages
- Bronchial Asthma: Mechanisms and Therapeutics by Earle B. Weiss on page 93, page 95, and page 133
- The Airway Epithelium (Lung Biology in Health and Disease) by Stephen Farmer on page 164, and page 243
- International Review of Cytology, Volume 207 by Kwang W. Jeon on page 164
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- Cell-Penetrating Peptides: Processes and Applications by Ulo Langel in Front Matter
- Neurotransmitter Receptors in Actions of Antipsychotic Medications (Handbooks in Pharmacology and Toxicology) by Michael S. Lidow in Front Matter
- Taxol: Science and Applications (Pharmacology and Toxicology) by Matthew Suffness in Front Matter
- Advances in Immunology, Volume 86 by Frederick W. Alt on page 37
- Cell Death: The Role of PARP by Csaba Szabo in Front Matter
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