Providing a broad overview of basic and clinical aspects of alpha 1-antitrypsin (a 1AT) deficiency, this up-to-date reference discusses the complex pathobiological processes underlying the pathogenesis of a1AT deficiency, describes the a1AT gene and its promoter, and details specific therapies to prevent the major clinical manifestations of the disorder.
Alpha 1 - Antitrypsin Deficiency
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Inside This Book
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First Sentence:
Alpha 1-antitrypsin (1AT) deficiency is a common hereditary disorder characterized by a reduction of serum levels of 1AT, emphysema, and liver disease (1-8). Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
intravenous augmentation therapy, nonindex cases, peptidyl carbamates, beta ribbon, bone marrow cell differentiation, unrecognized inherited disorder, human leukocyte elastase, turkey ovomucoid inhibitor, destructive lung disease, hepatic cell lines, neutrophil elastase gene, severe alpha, bilateral lung transplantation, canonical conformation, other serpins, porcine pancreatic elastase, human neutrophil elastase, deficient variant, intermediate alpha, peptide chloromethyl ketones, obstructive impairment, protein proteinase inhibitors, trifluoromethyl ketones, inhibitor phenotypes, biochemical efficacy Key Phrases - Capitalized Phrases (CAPs): (learn more)
Respir Dis, Biol Chem, Clin Invest, New York, Hum Genet, Principal Investigator, Proc Natl Acad Sci, Mol Biol, Med Chem, United States, Biochem Biophys Res Commun, Physiol Chem, Mol Cell Biol, Van Thiel, Exp Med, Genes Dev, Acta Med Scand, Clin Lab Invest, Academic Press, Hoppe Seylers, National Institutes of Health, Nucleic Acids Res, Ann Intern Med, Biochim Biophys Acta, National Heart New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Alpha 1-antitrypsin (1AT) deficiency is a common hereditary disorder characterized by a reduction of serum levels of 1AT, emphysema, and liver disease (1-8). Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
intravenous augmentation therapy, nonindex cases, peptidyl carbamates, beta ribbon, bone marrow cell differentiation, unrecognized inherited disorder, human leukocyte elastase, turkey ovomucoid inhibitor, destructive lung disease, hepatic cell lines, neutrophil elastase gene, severe alpha, bilateral lung transplantation, canonical conformation, other serpins, porcine pancreatic elastase, human neutrophil elastase, deficient variant, intermediate alpha, peptide chloromethyl ketones, obstructive impairment, protein proteinase inhibitors, trifluoromethyl ketones, inhibitor phenotypes, biochemical efficacy Key Phrases - Capitalized Phrases (CAPs): (learn more)
Respir Dis, Biol Chem, Clin Invest, New York, Hum Genet, Principal Investigator, Proc Natl Acad Sci, Mol Biol, Med Chem, United States, Biochem Biophys Res Commun, Physiol Chem, Mol Cell Biol, Van Thiel, Exp Med, Genes Dev, Acta Med Scand, Clin Lab Invest, Academic Press, Hoppe Seylers, National Institutes of Health, Nucleic Acids Res, Ann Intern Med, Biochim Biophys Acta, National Heart New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 100
books:
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- Lung Transplantation by G. a. Patterson on 4 pages
- Metabolic Basis of Inherited Disease by John B. Stanbury on page 13, page 56, and page 238
- Regulation of Matrix Accumulation (Biology of Extracellular Matrix) by Robert Mecham on page 72, and page 140
- Acute Respiratory Failure by Roger C. Bone in Front Matter (1), and Front Matter (2)
- Liver Transplantation (Clio Chirurgica, Vol 15) by Thomas E. Starzl on page 371, and page 378
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