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Amyloid, Prions, and Other Protein Aggregates, Volume 309 (Methods in Enzymology) [Hardcover]

John N. Abelson (Editor), Melvin I. Simon (Editor), Ronald Wetzel (Editor)


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Book Description

September 28, 1999 0121822109 978-0121822101 1
This volume includes a core of methodologies to attack the unique experimental problems presented by protein misassembly. Emphasis is on human biology applications, the area in which there is the most interest, in which most of the work has already been done, and in which there is the best evidence for the structural sophisitication of the protein aggregates.
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

Editorial Reviews

Review

Praise for the Series
"The Methods in Enzymology series represents the gold-standard."
--NEUROSCIENCE
"Incomparably useful."
--ANALYTICAL BIOCHEMISTRY
"It is a true 'methods' series, including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each page."
--BIO/TECHNOLOGY
"The series has been following the growing, changing and creation of new areas of science. It should be on the shelves of all libraries in the world as a whole collection."
--CHEMISTRY IN INDUSTRY
"The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced."
--AMERICAN SOCIETY OF MICROBIOLOGY NEWS
"If we had some way to find the work most often consulted in the laboratory, it could well be the multi-volume series Methods in Enzymology...a great work."
--ENZYMOLOGIA
"A series that has established itself as a definitive reference for biochemists."
--JOURNAL OF CHROMATOGRAPHY

From the Publisher

Praise for the Series "The Methods in Enzymology series represents the gold-standard." (Neuroscience)

"Incomparably useful." (Analytical Biochemistry)

"...including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each page." (Bio/Technology)

"...It should be on the shelves of all libraries in the world as a whole collection." (Chemistry in Industry)

"The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation..." (American Society of Microbiology News)

"If we had some way to find the work most often consulted in the laboratory, it could well be...Methods in Enzymology." (Enzymologia)

"A series that has established itself as a definitive reference for biochemists." (Journal of Chromatography)


Product Details

  • Hardcover: 820 pages
  • Publisher: Academic Press; 1 edition (September 28, 1999)
  • Language: English
  • ISBN-10: 0121822109
  • ISBN-13: 978-0121822101
  • Product Dimensions: 9.3 x 6.4 x 1.6 inches
  • Shipping Weight: 3.1 pounds
  • Amazon Best Sellers Rank: #3,222,104 in Books (See Top 100 in Books)

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Inside This Book (learn more)
First Sentence:
The staining reaction given by amyloid after treatment with iodine was often used in the earlier studies of amyloidosis, and amyloid is still to this date identified by its characteristic histological staining reactions. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
fibril isolates, amyloidogenic fold, amyloid template, amyloid fibril extension, native tailspikes, deposition assays, filter retardation assay, direct fit method, fibril content, tailspike polypeptide chains, normal human tau, peptide batches, vivo amyloid fibrils, spectral shift assay, fibril samples, tailspike protein, amyloidotic tissue, mixed disulfide derivative, amyloid assembly, synthetic fibrils, emission band width, aggregation intermediates, fibril nucleation, protein adsorption studies, fibril elongation
Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Nate Acad, Academic Press All, Methods Enzymol, Amyloid Int, Brain Res, Plenum Press, Boehringer Mannheim, Colloid Interface Sci, Bence Jones, Cell Biol, Coomassie Brilliant Blue, National Institutes of Health, Applied Biosystems, Nature Genet, Preventing Aggregate Formation, San Diego, Amersham Pharmacia Biotech, Boca Raton, Free Radic, Medical Research Council, Nature Struct, Vector Laboratories, Acta Neuropathol, Costa Mesa
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