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Amyotrophic Lateral Sclerosis [Hardcover]

Robert H. Brown Jr. (Author), Vincent Meininger (Author), Michael Swash (Author)

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Book Description

January 2000
Amyotrophic lateral sclerosis or motor neurone disease is one of the most debilitating and devastating of the neurological diseases with an incidence of about 1:100,000 In 26 chapters divided into five sections, this book examines all aspects of ALS from pathology to patient care and provides the reader with a ready reference to help with the relentless difficulties encountered in patient diagnosis and treatment

Editorial Reviews

From The New England Journal of Medicine

Amyotrophic lateral sclerosis is a progressive, paralyzing illness that is invariably fatal. It has been neglected until recently because there was only a poor understanding of pathogenesis and no treatment. Physicians often experience a sense of helplessness and frustration in conveying the diagnosis truthfully to patients and in helping them to cope with advancing disability and the prospect of death.

This book is an excellent review of amyotrophic lateral sclerosis with respect to clinical features, pathological findings, functional and physiologic studies, pathogenesis, therapeutic approaches, and patient care. It is an international effort, with its three editors from the United States, France, and the United Kingdom and 57 other contributors, all of whom are acknowledged experts in the field. It is a credit to the editors that the various chapters read seamlessly, with little sign of the multiple authorship. In addition, this is a handsome book with an excellent typeface.

All of the issues surrounding amyotrophic lateral sclerosis are dealt with in depth; a thought-provoking chapter covers the controversial subjects of physician-assisted suicide and euthanasia. I strongly recommend this compendium to neurologists and other physicians who provide care for patients with this illness.

Austin J. Sumner, M.D.
Copyright © 2000 Massachusetts Medical Society. All rights reserved. The New England Journal of Medicine is a registered trademark of the MMS.


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Inside This Book (learn more)
First Sentence:
The nomenclature of disorders of the motor system can be confusing (Table 1.1). Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
motor neuron cell death, motor neurone injury, bulbar score, sporadic amyotrophie lateral sclerosis, post symptom onset, argument from double effect, diminished penetrance, neuron disease spinal cord, arm megascore, inclusion dementia, drop from baseline, familial amyotrophie lateral sclerosis, unit number estimates, extremity assistive devices, familial motor neuron disease, lateral sclerosis functional rating scale, motor neuron destruction, human motor neuron disease, human motor neurones, neuron cell line, amyotrophic lateral sclerosis mortality, conglomerate inclusions, juvenile muscular atrophy, juvenile amyotrophic lateral sclerosis, dismutase gene mutations
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Ann Neurol, Neurol Sci, Neurol Neurosurg Psychiatry, Proc Natl Acad Sci, Arch Neurol, Muscle Nerve, New York, Brain Res, Neurosci Lett, Acta Neurol Scand, Acta Neuropathol, Ben Hamida, Neuropathol Exp Neurol, Cell Biol, Hum Mol Genet, Gouri Devi, Rev Neurol, Electroencephalogr Clin Neurophysiol, Neuropatbol Exp Neurol, Adv Neurol, Hum Genet, Nat Genet, Acta Neuropatbol, Comp Neurol, Neurol Clin
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