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Breath Analysis For Clinical Diagnosis & Therapeutic Monitoring (With Cd-Rom)

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Exhaled breath analysis is a new technique for medical diagnosis with
great future potential.

Already in clinical use is a 13C-urea based breath test for infection
with helicobacter pylori (causing gastric ulcer and gastric cancer).
Another clinically used test is the hydrogen breath test for fructose or
lactose malabsorption. A breath test for dihydropyrimidine dehydrogenase
deficiency is presently introduced into clinical testing (this is
important because persons suffering from this deficiency should not get
cancer treatment with 5-fluorouracil). A breath test for heart
transplant rejection, based on endogenously produced methylated
hydrocarbons has been approved by FDA. The determination of nitric oxide
in exhaled breath (from the upper airways) is used with asthma patients.

Exhaled breath analyis is expected to have an enormous impact on medical
diagnostic techniques in the next decade. It is non-invasive,
comparatively cheap, and analytical techniques have the potential of
miniaturization (leading to matchbox-size analytical devices which can
be used by medical practioners in daily routine).

The present book is the only overview of all applications of exhaled
breath analysis and all different analytical techniques used in the
field. Apart from excellent contributions it has a very carefully
prepared index which allows quick search (and, in addition, the book is
delivered with an electronic fully searchable version on CD-ROM).