Analysis of Multifactorial Diseases examines the evidence of genetic factors that increase susceptibility to a range of complex diseases and describes the approaches taken to identify these genes. It reviews the successes and failures and examines whether there are any general conclusions to be drawn from this current range of approaches.
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From the Back Cover
Analysis of Multifactorial Disease describes the approaches taken to identify the genes that confer susceptibility to a range of 'complex' diseases, which do not follow standard Mendelian principles. The evidence for genetic factors in diseases such as rheumatoid arthritis, epilepsy, diabetes, Alzheimer's disease, asthma and ischemic heart disease is considered. Each chapter reviews both the successes and failures of current approaches, indicates where general conclusions can be drawn, and examines how multifactorial diseases can be studied more effectively in the future.
The book is not a manual of procedures, but a comprehensive review of the current state of the art. The work of both clinicians and researchers can be improved by understanding the approaches used to analyze other 'complex' diseases and, as such, Analysis of Multifactorial Disease is the most up-to-date reference source for researchers and clinicians alike. --This text refers to the Paperback edition.
The book is not a manual of procedures, but a comprehensive review of the current state of the art. The work of both clinicians and researchers can be improved by understanding the approaches used to analyze other 'complex' diseases and, as such, Analysis of Multifactorial Disease is the most up-to-date reference source for researchers and clinicians alike. --This text refers to the Paperback edition.
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First Sentence:
This chapter reviews aspects of molecular genetics and DNA technology from their perspective as tools for the study of populations. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
optimal family structure, prostate cancer susceptibility locus, affected sibpairs, replicating linkage claims, complex segregation analyses, candidate gene association studies, prostate cancer families, candidate gene studies, whole genome screens, diabetes susceptibility genes, average sharing, disease susceptibility locus, susceptibility variants, marker allele frequencies, insulin gene region, nonparametric linkage analysis, intermediate traits, affected relative pairs, genetically complex traits, maximum lod score, diabetic fathers, idiopathic generalized epilepsy, affected sib pairs, susceptibility loci, dna pooling Key Phrases - Capitalized Phrases (CAPs): (learn more)
Nature Genet, Pima Indians, Allergy Clin, Care Med, Diabetes Care, New York, Scientific Publishers Ltd, Analysis of Multifactorial Disease, Mexican Americans, Oxford University Press, Delgado Escueta, Nail Acad, Natl Acad, Arthritis Rheum, Cancer Res, Genome Res, Tybjaerg Hansen, American Psychiatric Press, Brain Res, Mental Disorders, Psychiatry Res, Acids Res, Cancer Inst, Epileptic Syndromes, European Americans Abnormal New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
This chapter reviews aspects of molecular genetics and DNA technology from their perspective as tools for the study of populations. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
optimal family structure, prostate cancer susceptibility locus, affected sibpairs, replicating linkage claims, complex segregation analyses, candidate gene association studies, prostate cancer families, candidate gene studies, whole genome screens, diabetes susceptibility genes, average sharing, disease susceptibility locus, susceptibility variants, marker allele frequencies, insulin gene region, nonparametric linkage analysis, intermediate traits, affected relative pairs, genetically complex traits, maximum lod score, diabetic fathers, idiopathic generalized epilepsy, affected sib pairs, susceptibility loci, dna pooling Key Phrases - Capitalized Phrases (CAPs): (learn more)
Nature Genet, Pima Indians, Allergy Clin, Care Med, Diabetes Care, New York, Scientific Publishers Ltd, Analysis of Multifactorial Disease, Mexican Americans, Oxford University Press, Delgado Escueta, Nail Acad, Natl Acad, Arthritis Rheum, Cancer Res, Genome Res, Tybjaerg Hansen, American Psychiatric Press, Brain Res, Mental Disorders, Psychiatry Res, Acids Res, Cancer Inst, Epileptic Syndromes, European Americans Abnormal New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 42
books:
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cites this book:
- Genetic Approaches to Mental Disorders (American Psychopathological Association) by Elliot S. Gershon on 4 pages
- Math Master Pharmaceutical Calculations For The Allied-health Professional: A Competency-based Text And Workbook In Pharmaceutical Mathematics by Noah Reifman on page 122, page 124, and page 128
- The Genetics of Mood Disorders (Johns Hopkins Series in Contemporary Medicine and Public Health) by Dr. Ming T. Tsuang MD PhD DSc on page 195, and page 306
- Human Molecular Genetics, Third Edition by Tom Strachan in Front Matter, and page 13
- Seminars in Psychiatric Genetics (College Seminars Series) by Peter McGuffin on page 211, and page 305
See all 42 books this book cites
- Genetic Dissection of Complex Traits, Volume 42 (Advances in Genetics) by D. C. Rao on page 64, and page 112
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