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Analytical Molecular Biology
 
 
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Analytical Molecular Biology [Spiral-bound]

G. SAUNDERS (Author), H. PARKES (Author)

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Book Description

0854044728 978-0854044726 March 30, 1999 1
In spite of the wide variety and complexity of biological materials, nucleic acids are ubiquitous. DNA is becoming the bioanalyte of choice due to the vast amount of information embedded in its sequence, its robust chemical nature and the range of highly sensitive analytical techniques that have been developed. The results of such analyses can have an important impact on our society both commercially and in terms of the quality of life. Absolute confidence in the data generated is therefore of the utmost importance. This book, produced by LGC as part of the VAM (Valid Analytical Measurement) Programme, introduces the issues of validation and quality to the bioanalytical community, specifically addressing DNA-based analyses. It aims to raise awareness of the factors that can influence the validity of DNA analysis and the production of quality data. Emphasis is placed on VAM principles, as well as additional challenges that are associated with the analysis of real samples, for example, complex food matrices or forensic samples that have been subjected to environmental insult. Information is collated from a variety of sources including literature, discussions and LGC research, and offers constructive advice where possible.

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Inside This Book (learn more)
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
hybridisation rate, analytical molecular biology, dye primer chemistry, different thermal cyclers, membrane hybridisation, fluorescent enhancement, hybridisation solution, denaturation times, dye primers, membrane lysis, sequencing protocols, primer concentration, priming sites, free magnesium, successful amplification, ramp rate, exonuclease activity, sequencing reaction, primer design
Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Nucleic Acids Res, Fingerprinting Methods Based, Humana Press, Boca Raton, Stockton Press, Academic Press, Boehringer Mannheim, Laboratory Manual, Practical Approach, San Diego, Amplitaq Gold, Current Innovations, Essential Molecular Biology, Profiling Protocols, Analytical Molecular Biology Laboratory, Cold Spring Harbor, Molecular Cloning, Queen's Road
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