Biological Applications of Raman Spectroscopy Volume 1: Raman Spectra and the Conformations of Biological Macromolecules Edited by Thomas G. Spiro The first of the landmark volumes focusing on biological Raman applications, Volume 1 provides an incisive look at the current research surrounding the conformations of biological macromolecules. Volume 1 considers the varieties of macromolecules—proteins, nucleic acids, and lipids—in isolation and in the organized biological assemblies of ocular lenses, viruses, and membranes. The collective vibrational modes of macromolecules are considered theoretically, and there is a review of the promising area of vibrational optical activity. 1987 (0 471-81573-X) 352 pp. Volume 2: Resonance Raman Spectra of Polyenes and Aromatics The importance of the resonance Raman effect for biological applications is that it can provide dramatically increased sensitivity and selectivity The theory of the effect is presented in Volume 2, which also explores applications to rhodopsin, to the purine and pyrimidine bases of nucleic acids, to the peptide backbone and chromophoric side chains of proteins, to flavins, and, finally, to the introduction of resonance Raman labels into biological systems. 1987 (0 471-81574-8) 367 pp. Volume 3: Resonance Raman Spectra of Heme and Metalloproteins Heme proteins have provided an especially rich opportunity for Raman studies. Volume 3 describes in detail various aspects of work in this area, including applications to chlorophylls and nonheme metalloproteins. Coverage includes heme protein structure and the iron-histidine stretching mode; Raman scattering by cytochrome oxidase and by heme a model compounds; chlorophylls and the photosynthetic membrane; resonance Raman spectroscopy of blue copper proteins; and nonheme respiratory proteins. 1988 (0 471-81575-6) 565 pp.
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From the Publisher
Deals with the general analytical applicability of Raman spectroscopy as it relates to industrial uses. In many situations Raman spectroscopy is preferred over infrared spectroscopy because of its capability to do in situ analyses, to conduct dynamic studies, to work in aqueous solutions, and to obtain information on samples in any physical state of importance to properties.
From the Inside Flap
The exponential growth in the development of Raman spectroscopy is manifest in its almost limitless industrial uses. Its preeminence as an analytical method lies in its ability to perform in situ analysis, conduct dynamic studies, work in aqueous solutions, and obtain information on samples in any physical state. Analytical Raman Spectroscopy charts, through a series of contributed articles, the spectacular versatility of the method and its applications in semiconductor characterization, synthetic organic polymer analysis, organic and petrochemical analysis, heterogeneous catalysts, and biological studies. Chapters feature an outline structure which systematically details the critical aspects of each subject discussed.
- Components of modern Raman spectrometers
- Fourier transform Raman instrumentation
- Quantitative analysis by Raman spectroscopy
- Organic and petrochemical sample handling techniques and problem solving
- Time-resolved studies: examples of in situ studies of reacting systems
- Polymer analyses
- Chemical applications of gas-phase Raman spectroscopy
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