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Animal Models of Cognitive Impairment (Frontiers in Neuroscience) [Hardcover]

Edward D. Levin (Editor), Jerry J. Buccafusco (Editor)

Price: $162.95 & this item ships for FREE with Super Saver Shipping. Details
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Book Description

June 22, 2006 0849328349 978-0849328343 1
The costs associated with a drug’s clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models prior to the continued study of the drug in humans.

Featuring contributions from distinguished researchers in the field of cognitive therapy research, Animal Models of Cognitive Impairment examines some of the most popular and successful animal archetypes used in the context of drug discovery. It provides integrated coverage of the latest research concerning neuronal systems relevant to cognitive function and dysfunction, assimilating reviews of this research within the context of each chapter. This approach is unique in that it brings together molecular and neurochemical methodologies, behavioral applications in translational models, and clinical applications.

The book comprehensively discusses a wide variety of animal models of cognitive impairment, including genetic, lesion, pharmacological, and aging related impairments. It also explores the significance of this research in regards to the treatment of various addictions and disorders such as stroke, autism, Alzheimer’s, schizophrenia, and ADHD.

Edited by two renowned authorities in the field, Animal Models of Cognitive Impairment is a timely book that provides integrated coverage of cutting-edge research that concerns neuronal systems relevant to cognitive function and dysfunction.


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Inside This Book (learn more)
First Sentence:
Animal models of cognitive impairment are critically important for determining the neural bases of learning, memory, and attention. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
neurophysiological screen, ethanol interoceptive cue, mecamylamine doses, cognitive pharmacology, ethanol cue, cognitive assays, scrambled foot shock, telencephalic ablation, reinforcer ratios, retention latency, discriminative stimulus effects, nonspatial learning, developmental lead exposure, developmental exposure, discrimination reversal task, anterograde memory deficits, spatial discrimination reversal, spatial alternation task, delayed spatial alternation, interresponse times, blood lead concentrations, nonspatial memory, flavored diet, startle stimuli, relevant stimulus dimension
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Brain Res, New York, Behavioral Neuroscience, Academic Press, Neural Biol, Oxford University Press, Long-Evans Males, Wistar Males, Health Perspect, Raven Press, San Diego, Animal Behaviour, Behavioural Processes, Bruin Res, Cognitional Data, Journal of Neurobiology, Current Biology, Faroe Islands, Journal of Neuroscience, Sprague-Dawley Males, Assessments of Cognitive Deficits, California Verbal Learning Test, Hadj Tahar, National Academy Press, National Research Council
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