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Antibacterial Agents: Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications Paperback – July 23, 2012

ISBN-13: 978-0470972458 ISBN-10: 0470972459 Edition: 1st

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Editorial Reviews

From the Back Cover

Antibacterial Agents is an essential guide to an importantclass of chemotherapeutic drugs. In this full colour volume,compounds are organised according to their target, which helps thereader understand the mechanism of action of these drugs and howresistance can arise. Topics are presented using an integrated“lab-to-clinic” approach which covers drug discovery,source or synthesis, mode of action, mechanisms of resistance,clinical aspects including links to current guidelines, significantdrug interactions, cautions and contraindications, prodrugs andfuture improvements. This modern text summarises all the currentknowledge on antibacterial drugs, and each chapter includes fullcolour diagrams and a set of key points for easy reference.

Agents covered include:

  • agents targeting DNA - quinolone, rifamycin, and nitroimidazoleantibacterial agents
  • agents targeting metabolic processes -  sulfonamideantibacterial agents and trimethoprim
  • agents targeting protein synthesis - aminoglycoside, macrolideand tetracycline antibiotics, chloramphenicol, andoxazolidinones
  • agents targeting cell wall synthesis - β-lactam andglycopeptide antibiotics, cycloserine, isoniazid, anddaptomycin

Antibacterial Agents will find a place on the bookshelvesof students of pharmacy, pharmacology, pharmaceutical sciences,drug design/discovery, and medicinal chemistry, and as a benchreference for pharmacists and pharmaceutical researchers inacademia and industry.

--This text refers to the Hardcover edition.

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