As the field of antibody engineering continues its explosive growth, more and more scientists around the world are striving to keep up with the latest developments. Now in its second edition, Antibody Engineering is the perfect one-stop introduction to state-of-the-art technologies emerging in the field today. In presenting a practical overview of the engineering of recombinant human or mouse monoclonal antibodies, the book incisively addresses essential topics such as antibody structure relevant to antibody engineering, recombinatorial cDNA libraries, phage display, synthetic and humanized antibodies, engineering of affinity and biological effector functions, and plant, mammalian, and bacterial expression vectors and hosts. Antibody Engineering, Second Edition--written by leading experts and now thoroughly updated--is a unique resource for current information on the subject. It will be welcomed by researchers in immunology, biotechnology, molecular biology, and biochemistry.
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About the Author
Carl A.K. Borrebaeck is at University of Lund.
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Inside This Book
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First Sentence:
The remarkably diverse specificity of antibodies can now be explained both in genetic and structural terms. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
phagemid display library, fragment gene repertoires, appended restriction sites, mouse antibody genes, active chimeric antibody fragment, intercellular immunization, using mixed primers, cytosolic contaminants, mouse light chain, nonsuppressor strain, periplasmic inclusion bodies, phage antibody library, nonbinding phage, parental antibody, phagemid library, antibody domains, binding clones, combinatorial antibody libraries, lambda library, eluted phage, displaying antibody variable domains, pmol oligo, immunoglobulin variable domains, back primers, human light chains Key Phrases - Capitalized Phrases (CAPs): (learn more)
Acids Res, New England Biolabs, New York, San Diego, Laboratory Manual, Cell Biol, Methods Enzymol, Practical Approach, Cold Spring Harbor Laboratory Press, Protein Eng, Proteins Struct, Specifics of Method, Current Protocols, Grand Island, National Institutes of Health, Perkin Elmer, Plant Mol, Protein Sci New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
The remarkably diverse specificity of antibodies can now be explained both in genetic and structural terms. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
phagemid display library, fragment gene repertoires, appended restriction sites, mouse antibody genes, active chimeric antibody fragment, intercellular immunization, using mixed primers, cytosolic contaminants, mouse light chain, nonsuppressor strain, periplasmic inclusion bodies, phage antibody library, nonbinding phage, parental antibody, phagemid library, antibody domains, binding clones, combinatorial antibody libraries, lambda library, eluted phage, displaying antibody variable domains, pmol oligo, immunoglobulin variable domains, back primers, human light chains Key Phrases - Capitalized Phrases (CAPs): (learn more)
Acids Res, New England Biolabs, New York, San Diego, Laboratory Manual, Cell Biol, Methods Enzymol, Practical Approach, Cold Spring Harbor Laboratory Press, Protein Eng, Proteins Struct, Specifics of Method, Current Protocols, Grand Island, National Institutes of Health, Perkin Elmer, Plant Mol, Protein Sci New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 14
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25
books
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- Sequences of Proteins of Immunological Interest (6 Volume Set) by Elvin A. Kabat on 5 pages
- Molecular Cloning: A Laboratory Manual, Third Edition (3 volume set) by Joe Sambrook on page 130, page 360, and page 375
- Antibody Engineering: A Practical Guide (Breakthroughs in Molecular Biology) by Carl A.K. Borrebaeck on page 130, and page 156
- Protein Structure: A Practical Approach by T. E. Creighton on page 226
- Monoclonal Antibodies (Postgraduate Medical Science) by Mary A. Ritter on page 226
See all 14 books this book cites
- Antibody Engineering (Springer Lab Manuals) by Roland Kontermann on 4 pages
- Recombinant Antibodies for Cancer Therapy: Reviews and Protocols (Methods in Molecular Biology) by Martin Welschof on page 211, and page 233
- Cancer Therapy with Radiolabeled Antibodies by David M. Goldenberg on page 267, and page 270
- Structure of Antigens, Volume II by Marc H. V. Van Regenmortel on page 3, and page 28
- Recombinant Antibodies: Applications in Plant Science and Plant Pathology by Karen Harper on page 18, and page 100
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