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Anticancer Drugs from Animals, Plants, and Microorganisms [Hardcover]

George R. Pettit (Author), Fiona Hogan Pierson (Author), Cherry L. Herald (Author)


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Book Description

April 1994 0471036579 978-0471036579 1
Affords researchers ready access to a vast body of information on identifying and isolating natural anticancer agents… The authors open this valuable text/reference with an in-depth exploration of the vast potential of plant, animal, microorganism constituents as sources for new and effective anticancer, antiviral drugs. They update the literature on cancer-causing and related viruses with an emphasis on HIV. And they summarize the better known tumor promoters and carcinogens, and point out the fine line between antineoplastic and carcinogenic activity. The lion’s share of the book consists of an exhaustive compilation, in tabular form, of terrestrial and marine products. The first section covers terrestrial and marine plant and animal antineoplastic and cytotoxic constituents, organized by source. Within each chapter, entries are listed in order of molecular formula. Included are the more active synthetic and some semi synthetic analogs, with indications of which modifications are most likely to be useful. Also as an aid to quick reference, indexes provide access to entries by way of compound name, molecular weight, and species name. In the second section, the authors offer an exhaustive survey of marine plant and animal products, including both those with known biological activity and those without. As in the previous section, entries are listed according to molecular formula.

Editorial Reviews

From the Publisher

The main thrust of this volume is on the potential of animal, microorganism and plant constituents as sources for new and potentially useful anticancer, antiviral and other essential drugs to solve severe medical problems. Coverage includes updated data on cancer-causing and related human viruses with emphasis on HIV-1 infections, a summary of the better known tumor promoters and carcinogens, marine animal and plant biosynthetic products.

About the Author

George R. Pettit, PhD, is Dalton Professor of Cancer Research, Regent’s Professor of Chemistry, and Director of the Cancer Research Institute of Arizona State University. He has received numerous awards for his research into anticancer drugs, including an Outstanding Investigator Award from the National Cancer Institute and a Chemical Pioneer Award from the American Institute of Chemists. Fiona Hogan Pierson, PhD, is Assistant Research Specialist with the Cancer Research Institute of Arizona State University. She holds degrees in organic chemistry from University College Dublin, Ireland. Cherry L. Herald, PhD, is Research Professor and Associate Director of the Cancer Research Institute of Arizona State University. Dr. Herald holds degrees in chemistry and organic chemistry from Arizona State University.

Product Details

  • Hardcover: 688 pages
  • Publisher: Wiley-Interscience; 1 edition (April 1994)
  • Language: English
  • ISBN-10: 0471036579
  • ISBN-13: 978-0471036579
  • Product Dimensions: 10.2 x 7.3 x 1.4 inches
  • Shipping Weight: 3.2 pounds
  • Amazon Best Sellers Rank: #4,817,493 in Books (See Top 100 in Books)

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Inside This Book (learn more)
First Sentence:
The lethal threat posed by RNA-type viruses has been rapidly increasing. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
starfish egg assay, synthetic sterol, sea urchin egg assay, urchin assay, melting point, ascites carcinoma, biosynthetic products, corona virus, antifungal activity, antimicrobial activity, tubulin polymerization, antibacterial activity, analgesic activities, hepatoma cells
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Spectral Data, Japan Reference, Australia Reference, Organ Site, Animal Model, Italy Reference, Human Site, New Caledonia Reference, Fiji Reference, Great Barrier Reef, New Zealand Reference, Truk Reference, France Reference, Palau Reference, Canada Reference, Hawaii Reference, Bahamas Reference, British Columbia, Red Sea Reference, China Reference, California Reference, Guam Reference, India Reference, Mediterranean Reference, Sicily Reference
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