The availability today of a growing number of newly synthesized antihormones has provided a novel means of investigating the molecular actions of hormones and controlling contraception and hormone-dependent dysfunction. The contributors to this volume present the latest developments in the field of hormone antagonists, from both biological and clinical perspectives, with particular emphasis on steroid hormone structure and function. A feature of the book is the discussion of the mechanisms of action and effects of the antiglucocorticoid RU 38486, as well as the potential application of its dissociated parts for the treatment of hormone-dependent conditions including breast cancer and hypertension.
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