Antisense Oligodeoxynucleotides and Antisense RNANovel Pharmacological and Therapeutic Agents [Hardcover]

Benjamin Weiss (Editor)

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Book Description

ISBN-10: 0849385520 | ISBN-13: 978-0849385520 | Publication Date: November 30, 1997 | Edition: 1

This book is a practical, state-of-the-art treatise on antisense oligodeoxynucleotide and antisense RNA technology and the potential application of these strategies in therapeutics. Critical analyses of the specificity of the agents are featured, and the possibility of antisense oligomers acting through non-antisense mechanisms is considered. Novel Pharmacological and Therapeutic Agents cover: the history of early development of antisense oligodeoxynucleotides and their chemical modification to increase their stability, delivery and penetration into cells; Non-antisense effects of antisense oligonucleotides; Pharmacokinetic properties; In vitro and in vivo model systems; Clinical trials, and much more.

#outer_postBodyPS { display: none; } #psGradient { display: none; } #psPlaceHolder { display: none; } #psExpand { display: none; } This book is a practical, state-of-the-art treatise on antisense oligodeoxynucleotide and antisense RNA technology and the potential application of these strategies in therapeutics. Critical analyses of the specificity of the agents are featured, and the possibility of antisense oligomers acting through non-antisense mechanisms is considered. Novel Pharmacological and Therapeutic Agents cover: the history of early development of antisense oligodeoxynucleotides and their chemical modification to increase their stability, delivery and penetration into cells; Non-antisense effects of antisense oligonucleotides; Pharmacokinetic properties; In vitro and in vivo model systems; Clinical trials, and much more.

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Product Details

Hardcover: 272 pages
Publisher: CRC-Press; 1 edition (November 30, 1997)
Language: English
ISBN-10: 0849385520
ISBN-13: 978-0849385520
Product Dimensions: 10.5 x 7.5 x 0.8 inches
Shipping Weight: 1.6 pounds (View shipping rates and policies)
Amazon Best Sellers Rank: #6,546,953 in Books (See Top 100 in Books)

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