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Antiviral Methods and Protocols (Methods in Molecular Medicine)
 
 
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Antiviral Methods and Protocols (Methods in Molecular Medicine) [Hardcover]

Derek Kinchington (Editor), Raymond F. Schinazi (Editor)

Price: $125.00 & this item ships for FREE with Super Saver Shipping. Details
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Book Description

September 25, 1999 0896035611 978-0896035614 1
Experienced scientists describe-in an easily-followed format-their state-of-the-art techniques for evaluating antiviral compounds. The assays described include systems for investigating drugs used against herpesviruses, hepatitis viruses, human immunodeficiency viruses, human papillomaviruses, and influenza viruses. These well-tested methods range from cellular assays to some of the most up-to-date molecular approaches for identifying compounds that are active against viral enzymes and the development of viral resistance against drugs currently in use. Timely and comprehensive, Antiviral Methods and Protocols offers today's researchers in academia, clinical departments, and the pharmaceutical industry the powerful, reproducible, and novel methods needed to evaluate compounds effective against both acute and chronic infections.

Editorial Reviews

Review

"...will be of great benefit to all involved with antiviral development..." -Antiviral Research "...Together with some useful general discussions on safety and new approaches to antiviral research this volume offers extremely useful information for both the pharmaceutical industry and the academic researcher."-Microbiology Today "...the editors are to be congratulated for assembling an impressive array of experts in the field as authors for the chapters and the book should remain a valuable reference work for many years, despite the rapidly moving nature of the discipline." - Journal of Antimicrobial Chemotherapy

From the Back Cover

In Antiviral Methods and Protocols, experienced scientists describe-in an easily-followed format-their state-of-the-art techniques for evaluating antiviral compounds. The assays described include systems for investigating drugs used against herpesviruses, hepatitis viruses, human immunodeficiency viruses, human papillomaviruses, and influenza viruses. These well-tested methods range from cellular assays to some of the most up-to-date molecular approaches for identifying compounds that are active against viral enzymes and the development of viral resistance against drugs currently in use. The detailed protocols also discuss possible pitfalls and ways to overcome them. Timely and comprehensive, Antiviral Methods and Protocols offers today's researchers in academia, clinical departments, and the pharmaceutical industry the powerful, reproducible, and novel methods needed to evaluate compounds effective against both acute and chronic infections.

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Inside This Book (learn more)
First Sentence:
Viral diseases were largely untreatable 40 yr ago. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
appropriate enzyme concentration, hybridized counts, herpesvirus proteases, helicase assay, helicase reaction, capture oligo, monitoring drug resistance, microplate shaker, human cytomegalovirus protease, dot blotter, search for antiviral drugs, multichannel pipeter, enzyme dilution buffer, silica pellet, mycoplasma colonies, overlay medium, genome copy numbers, virus medium, twofold dilution series, gel soak, seeding medium, stain uptake, plaque reduction assay, cluster dish, drug medium
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Humana Press Inc, Molecular Medicine, Life Technologies, Evaluating Clinical Isolates, Boehringer Mannheim, Agents Chemother, Pharmacia Biotech, New York, Perkin Elmer, Risk Group, Safety Considerations, Antiviral Chem, Herpesvirus Protease Assays, Nucleic Acids Res, Retroviral Integrase, Antiviral Res, Becton Dickinson, Determination of Viral Infectivity, Polymerase Activities, Blood Kit, Compounds Against Recombinant, Current Protocols, Determination of Appropriate Enzyme Concentration, Hazard Group, Molecular Dynamics
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