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Applied Antisense Oligonucleotide Technology
 
 
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Applied Antisense Oligonucleotide Technology [Paperback]

Cy A. Stein (Editor), Arthur M. Krieg (Editor)

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Book Description

March 19, 1998 0471172790 978-0471172796 1
Applied Antisense Oligonucleotide Technology provides the basic concepts as well as the practical concerns associated with the use of antisense oligonucleotides to modify gene expression. Chapters include oligonucleotide chemistry, DNA triplex formation, delivery mechanisms, pharmocokinetics, toxicity, oligonucleotides.

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Editorial Reviews

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"This book will be most useful to workers in the field and advanced graduate students." --The Quarterly Review of Biology, June 1999

From the Publisher

Applied Antisense Oligonucleotide Technology provides the basic concepts as well as the practical concerns associated with the use of antisense oligonucleotides to modify gene expression. Chapters include oligonucleotide chemistry, DNA triplex formation, delivery mechanisms, pharmocokinetics, toxicity, oligonucleotides.

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Inside This Book (learn more)
First Sentence:
Oligonucleoside methylphosphonates are a class of nonionic oligonucleotide analogs. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
oxathiaphospholane method, thrombin binding aptamer, deoxyribonucleic guanidine, chimeric analogs, oligonucleoside methylphosphonates, oligodeoxyribonucleoside methylphosphonates, propyne analogs, methylphosphonate linkages, stereoregular oligo, potent antisense oligonucleotides, antisense activity, antisense oligonucleotide technology, nonantisense effects, extracted radioactivity, triplex formation, antisense mechanism, second generation antisense oligonucleotides, antisense potency, gene inhibition using antisense oligodeoxynucleotides, oligodeoxynucleotide analogues, diester structures, antisense gene inhibition, psoralen adducts, oligodeoxynucleoside methylphosphonates, internucleoside linkages
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Nucleic Acids Res, Antisense Res, Cancer Res, Tetrahedron Lett, Applied Antisense Oligonucleotide Technology, Nature Med, New York, Humana Press, Cell Biol, Nucleosides Nucleotides, Boca Raton, Bioconjugate Chem, Anti-Cancer Drug Design, Agents Chemother, Marked B-cell, Cold Spring Harbor, Genes Dev, Kidney Int, Macmillan Press, United States, Antisense Nucleic Acid Drug Dev, Brain Res, Isis Pharmaceuticals, Antiviral Res, Methods Enzymol
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