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Applied Microbial Physiology: A Practical Approach
 
 
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Applied Microbial Physiology: A Practical Approach [Paperback]

P. M. Rhodes (Editor), P. F. Stanbury (Editor)

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Book Description

0199635773 978-0199635771 October 9, 1997
In recent years, the rapid growth in biotechnology has led to an upsurge in interest in microbial technology among biochemists, molecular biologists, geneticists, virologists, endocrinologists, and clinicians. Advances in microbial physiology have helped scientists realize a rational approach to optimization of product yield based on analysis of cultures, growth kinetics, and biochemical pathways; its applications also extend to microbiology and biotechnology. This book arises from both the need for practical information to enable the isolation, handling, and culture of organisms, and the necessity to generate and analyze data enabling the development of the process. Chapters cover the "husbandry" of microbiology, the generation of data by chemical and physical analysis, and the interpretation of such data. This is considered from two points of view. On one hand, kinetic analyses of growth and product formation have frequently illuminated the development of fermentation processes. More recently, though, the analysis of the flux of metabolites through intermediate biochemical pathways has shown up important facts in metabolic engineering through the application of molecular biology techniques in microbial physiology. This is a useful resource and guide to the successful culture of microorganisms in pure form, optimizing the culture conditions and the scaling-up process to enable more detailed study.

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Editorial Reviews

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"The editors note that during the rapid development of biotechnology, scientists from many biological or medical disciplines have come to rely on the use of microorganisms to produce substances of commercial value. In many cases, the scientists do not have the training of a microbiologist, and this book seeks to provide the type of information that will enable them to move from research results to the point of production. . . . The contributors are well-known scientists in their fields. There are two appendixes, a useful list of 66 suppliers of equipment and chemicals . . . and an extensive list of the larger culture collections around the world. . . . All of the chapters are well written, and the book gives a good general perspective of the immense complexity of biotechnology."--The Quarterly Review of Biology


About the Author

Dr P. Malcolm Rhodes, Bioscot Ltd, King's Buildings, West Mains Road, Edinburgh EH9 3JF. Tel: 0131 662 4551. Fax: 0131 662 4279. Dr Peter Stanbury, Dept of Biosciences, University of Hertfordshire, Hatfield Campus, Hatfield, Herts AL10 9AD

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Inside This Book (learn more)
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First Sentence:
It is essential when working with microorganisms that the strains employed are representative of the species and possess the full range of properties typical of the organism. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
anaplerotic provision, continuous culture work, acetate excretion, throughput diagram, biotechnological process analysis, excrete acetate, resazurin solution, triplicate standards, sample manifold, monitoring reagent, inoculation port, laboratory fermenters, medium optimization, flux analysis, suitable growth medium, dry cell weight, reverse osmosis water, coli growing, biomass determination, trace element solution, vent gas, cultivation medium, serum bottles, sample valve, undissolved solids
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Academic Press, Citrate Succinyl, Boca Raton, Malachite Green, Plenum Press, Braun Biotech, Citrate Succinate, John Wiley, New York, Penol Pyruvate, Difco Bacto, Blackwell Scientific Publications, Continued Method, Courtesy Mettler Toledo, International Mycological Institute, Vacuum Industrial Products Ltd
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