Applied Thin-Layer Chromatography: Best Practice and Avoidance of Mistakes [Hardcover]

Elke Hahn-Deinstrop (Author)

Book Description

Publication Date: January 8, 2007 | ISBN-10: 3527315535 | ISBN-13: 978-3527315536 | Edition: 2

Thin layer chromatography (TLC) is a powerful, fast and inexpensive analytical method. It has proven its usefulness in pharmaceutical, food and environmental analysis. This new edition features a completely revised chapter on documentation, now including the use of digital cameras. Selected new sorbents and instruments are also introduced.

Why has the prior edition been successful? All steps of the analytical procedure are clearly explained, starting with the choice of a suitable TLC technique and ending with data evaluation and documentation. Special emphasis is put on the proper choice of materials for TLC. Properties and functions of various materials and the TLC equipment are described, covering e. g. precoated layers, solvents and developing chambers, and including information on suppliers. Many practical hints for trouble shooting are given. All this is illustrated with numerous coloured figures.

How to use TLC in compliance with GLP/GMP regulations is described in detail, including the required documentation. Therefore the reader can very easily compile his own standard operating procedures.

Editorial Reviews

Review

"…an excellent practical guide to the utilization of this useful analytical procedure." (Journal of Hazardous Materials, June 25, 2007)

"This impressive book thoroughly discusses a subject not usually covered thoroughly in the analytical chemistry literature." (CHOICE, June 2007)

From the Back Cover

Thin-layer chromatography (TLC) is a powerful, fast and inexpensive analytical method, which has proven its effectiveness in the analysis of pharmaceuticals, food and the environment. This new edition of the practical guide to TLC includes a completely revised chapter on documentation, which now covers the use of digital cameras, while selected new sorbents and instruments are also introduced.

This edition retains the successful features of its predecessor:

• Clear explanation of all steps in the analytical procedure, starting with the choice of a suitable TLC technique and finishing with data evaluation and documentation.
• Special emphasis on the correct choice of materials for TLC. Properties and functions of various materials and the TLC equipment are described, covering precoated layers, solvents and developing chambers, including information on suppliers, among others.
• Many practical hints for troubleshooting.
• Detailed description of using TLC in compliance with GLP/GMP regulations, including the required documentation , allowing readers to easily compile their own standard operating procedures.
• Numerous color illustrations.

From the reviews of the first edition:

"A clear, step-by-step practical guide to TLC, covering every stage of the process from plate selection and sample application to development and quantification. At every stage potential pitfalls are clearly signposted and each chapter contains a profusion of pracitcal tips. Even a seasoned TLC practitioner should find something of use or interest in this book which complements most existing texts."
—The Analyst

See all Editorial Reviews

Product Details

• Hardcover: 330 pages
• Publisher: Wiley-VCH; 2 edition (January 8, 2007)
• Language: English
• ISBN-10: 3527315535
• ISBN-13: 978-3527315536
• Product Dimensions: 7 x 0.8 x 9.7 inches
• Shipping Weight: 1.6 pounds (View shipping rates and policies)
• Amazon Best Sellers Rank: #3,579,846 in Books (See Top 100 in Books)

More About the Author

Discover books, learn about writers, read author blogs, and more.