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Chemical Approaches to the Synthesis of Peptides and Proteins (New Directions in Organic & Biological Chemistry) [Hardcover]

Paul Lloyd-Williams (Author), Fernando Albericio (Author), Ernest Giralt (Author)

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Book Description

ISBN-10: 0849391423 | ISBN-13: 978-0849391422 | Publication Date: July 23, 1997 | Edition: 1

The latest, most efficient methods for the synthesis of peptides and proteins. This reference evaluates the most important synthesis methods available today, and also considers methods that show promise for future applications. This text describes the state of the art in efficient synthetic methods for the synthesis of both natural and artificial large peptide and protein molecules. Subjects include an introduction to basic topics, linear solid-phase synthesis of peptides, peptide synthesis in solution, convergent solid-phase synthesis, methods for the synthesis of branched peptides, formation of disulfide bridges, and more. The book emphasizes strategies and tactics that must be considered for the successful synthesis of peptides.

#outer_postBodyPS { display: none; } #psGradient { display: none; } #psPlaceHolder { display: none; } #psExpand { display: none; } The latest, most efficient methods for the synthesis of peptides and proteins. This reference evaluates the most important synthesis methods available today, and also considers methods that show promise for future applications. This text describes the state of the art in efficient synthetic methods for the synthesis of both natural and artificial large peptide and protein molecules. Subjects include an introduction to basic topics, linear solid-phase synthesis of peptides, peptide synthesis in solution, convergent solid-phase synthesis, methods for the synthesis of branched peptides, formation of disulfide bridges, and more. The book emphasizes strategies and tactics that must be considered for the successful synthesis of peptides.

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Product Details

Hardcover: 304 pages
Publisher: CRC-Press; 1 edition (July 23, 1997)
Language: English
ISBN-10: 0849391423
ISBN-13: 978-0849391422
Product Dimensions: 9.3 x 6.2 x 0.9 inches
Shipping Weight: 1.2 pounds (View shipping rates and policies)
Amazon Best Sellers Rank: #2,061,256 in Books (See Top 100 in Books)
- #39 in Books > Professional & Technical > Professional Science > Chemistry > Organic > Synthesis

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Inside This Book (learn more)

First Sentence:
Proteins play a crucial role in almost all fundamental processes in the living cell. Read the first page

Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
protected peptide segments, amide bond protection, classical peptide synthesis, final acidolysis, treatment with liquid hydrogen fluoride, citraconyl anhydride, uronium reagents, directed disulfide formation, internal reference amino acid, protease analogue, acidolytic conditions, overall protection scheme, peptide hydrazide, chemical ligation, benzotriazolyl esters, acidolytic removal, cesium carboxylate, segment coupling, first disulfide bridge, aspartimide formation, side chain protection, amino component, acidolytic cleavage, diketopiperazine formation, uronium salts

Key Phrases - Capitalized Phrases (CAPs): (learn more)
Protein Res, Tetrahedron Lett, European Peptides Symposium, American Peptides Symposium, New York, Perkin Trans, Academic Press, Solid Phase Synthesis, Liebigs Ann, Mayflower Worldwide Ltd, Nvoc Nvoc, Ann Arbor, Pierce Chemical Company, Bioconjugate Chem, Major Methods of Peptide Bond Formation, Special Methods, Acta Chem, Cam Cam, Georg Thieme Verlag, John Wiley, N-terminal Cys, Walter de Gruyter, Angew Chem, Intercept Ltd, Bzl Bzl

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Citations (learn more)

This book cites 18 books:

Peptide Synthesis (Interscience monographs on organic chemistry) by Miklos Bodanszky on page 130, and page 134
New York (Land of Liberty) by Ellen Sturm on page 83
The Anomeric Effect (New Directions in Organic and Biological Chemistry) by Eusebio Juaristi in Front Matter
Cyclization Reactions (New Directions in Organic & Biological Chemistry) by C. Thebtaranonth in Front Matter
Principles of Peptide Synthesis (Springer Laboratory) by Milkos Bodanszky on page 134

See all 18 books this book cites

10 books cite this book:

Polymer Chemistry: An Introduction by Malcolm P. Stevens in Back Matter
Handbook of Cell-Penetrating Peptides, Second Edition (Pharmacology and Toxicology: Basic and Clinical Aspects) by Ulo Langel on page 78
Synthetic Peptides: A User's Guide (Advances in Molecular Biology) by Gregory Grant on page 197
Peptide Antibiotics: Discovery Modes Of Action And Applications by Christopher Dutton on page 37
Synthetic Peptides as Antigens, Volume 28 (Laboratory Techniques in Biochemistry and Molecular Biology) by S. Muller in Back Matter

See all 10 books citing this book

Books on Related Topics (learn more)

Organic Synthesis on Solid Phase by Florencio Zaragoza D�rwald

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Fmoc Solid Phase Peptide Synthesis by W. C. Chan

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Amino Acid and Peptide Synthesis by John Jones

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Greene's Protective Groups in Organic Synthesis by Peter G. M. Wuts

Discusses:

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