From the Manufacturer
"Miskatonic University is a place of learning and discovery. However, the diligent researchers of the acclaimed college are about to uncover a host of terrible mysteries that should have remained buried...Build upon your Arkham Horror experience with Miskatonic Horror, a unique expansion that enhances your existing Arkham Horror expansions! With nearly 450 new cards, Miskatonic Horror adds new Mythos cards and Location cards for Dunwich, Kingsport, and Innsmouth, as well as new cards for Gates, Epic Battles, Relationships, Injuries, Madness, Skills, Blights, and much more! Not only does Miskatonic Horror enhance all of the Arkham Horror expansions, it also contains materials that can supplement the base game, such as new player reference sheets, the Institution variant, and a variety of new cards. The professors of Miskatonic University seek to define their world through science... but their hubris will soon lead them to discoveries too horrific to fathom."
A recent find at Miskatonic University has unearthed even more mysteries pertaining to the strange happenings in Arkham, Massachusetts. While the worshippers of the Ancient One grow in strength, the stalwart defenders of this sleepy town are put to the ultimate test.
Miskatonic Horror is a new type of Arkham Horror expansion that builds upon the materials found in the ample library of other Arkham Horror expansions. While the components and rules found in Miskatonic Horror can be enjoyed with only the Arkham Horror base game, the more expansions you incorporate, the more aspects of Miskatonic Horror you can enjoy.