This vitally important reference traces the progress of antiarrhythmic drug trials and treatment methods-from the vantage point of the clinicians who designed and conducted the studies to objective views of the strengths and weaknesses of the results, identifying unresolved questions or newly created issues. Reviews significant studies in chronological order-providing a clear, informative account of how current thinking about arrhythmia treatment has evolved. Written by over 35 leading experts in the field, Clinical Trials on the Treatment of Arrhythmias · emphasizes the need for science-based therapeutics and rigorously controlled clinical trials of drugs and implantable devices · compares electrocardiographic monitoring with electrophysiological techniques for arrhythmia management · analyzes the landmark Cardiac Arrhythmia Suppression Trial (CAST) · evaluates the effectiveness of amiodarone · describes sodium and potassium channel blockers and the development of drugs that slow conduction velocity and prolong repolarization and refractoriness · investigates the effects of the d-isomer of sotalol on mortality · critiques studies on the established efficacy of implantable devices versus amiodarone to benefit post-bypass surgery patients · and more! Containing over 600 literature citations, Clinical Trials on the Treatment of Arrhythmias is an invaluable resource for cardiologists and cardiovascular specialists, pharmacologists, pharmaceutical researchers, and graduate and medical school students in these disciplines.
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Editorial Reviews
Review
...Woolsey and Singh focus on the landmark clinical trials that have been conducted to evaluate various antiarrhythmic therapies.
...[a] valuable synthesis of large amounts of information...a good addition to the cardiologist's library.
- Texas Heart Institute Journal
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Inside This Book
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First Sentence:
IMPACT (1) was published in 1984. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
arrhythmia qualifier, electrocardiographic monitoring trial, antiarrhythmic drug group, placebo antiarrhythmic coronary trial, antiarrhythmic therapy guided, resuscitated ventricular fibrillation, defibrillator group, electrophysiologic study versus electrocardiographic monitoring, amiodarone group, relationships among ventricular arrhythmias, amiodarone arm, asymptomatic complex ventricular arrhythmias, proarrhythmic mechanism, drug limb, nonarrhythmic death, repetitive ventricular premature depolarizations, prophylactic antiarrhythmic drug therapy, serial drug testing, nonsudden cardiac death, patients with inducible, arrhythmic mortality, empiric amiodarone, ventricular extrastimuli, conventional antiarrhythmic drugs, complex cardiac arrhythmias Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York Heart Association, Multicenter Unsustained Tachycardia Trial, Prog Cardiovasc Dis, Veterans Affairs, United States, Amiodarone Trials Meta-Analysis Investigators, Blood Institute, Cardiac Arrest Study Hamburg, National Heart, Survival Trial of Antiarrhythmic Therapy, Grupo de Estudio de la Sobrevida, Insuficiencia Cardiaca, Canadian Implantable Defibrillator Study, Controlled Clin Trials, European Myocardial Infarct Amiodarone Trial Investigators, Cardiac Arrhythmia Pilot Study, Eur Heart, Multicenter Automatic Defibrillator Implantation Trial Investigators, Basel Antiarrhythmic Study of Infarct Survival, Coronary Artery Surgery Study, National Institutes of Health, North American, Ann Intern Med, University of Washington, Pacing Clin Electrophysiol New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
IMPACT (1) was published in 1984. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
arrhythmia qualifier, electrocardiographic monitoring trial, antiarrhythmic drug group, placebo antiarrhythmic coronary trial, antiarrhythmic therapy guided, resuscitated ventricular fibrillation, defibrillator group, electrophysiologic study versus electrocardiographic monitoring, amiodarone group, relationships among ventricular arrhythmias, amiodarone arm, asymptomatic complex ventricular arrhythmias, proarrhythmic mechanism, drug limb, nonarrhythmic death, repetitive ventricular premature depolarizations, prophylactic antiarrhythmic drug therapy, serial drug testing, nonsudden cardiac death, patients with inducible, arrhythmic mortality, empiric amiodarone, ventricular extrastimuli, conventional antiarrhythmic drugs, complex cardiac arrhythmias Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York Heart Association, Multicenter Unsustained Tachycardia Trial, Prog Cardiovasc Dis, Veterans Affairs, United States, Amiodarone Trials Meta-Analysis Investigators, Blood Institute, Cardiac Arrest Study Hamburg, National Heart, Survival Trial of Antiarrhythmic Therapy, Grupo de Estudio de la Sobrevida, Insuficiencia Cardiaca, Canadian Implantable Defibrillator Study, Controlled Clin Trials, European Myocardial Infarct Amiodarone Trial Investigators, Cardiac Arrhythmia Pilot Study, Eur Heart, Multicenter Automatic Defibrillator Implantation Trial Investigators, Basel Antiarrhythmic Study of Infarct Survival, Coronary Artery Surgery Study, National Institutes of Health, North American, Ann Intern Med, University of Washington, Pacing Clin Electrophysiol New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 13
books:
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cites this book:
- Sudden Cardiac Death (Cardiology, Vol 74, Suppl 2) by Robert J. Myerburg on page 82, and page 241
- Heart Attack (Thorsons Health Series) by David Lewis on page 126, and page 214
- Human Rights: v. 1: Acts, Statutes and Constitutional Provisions by D. N. Gupta on page 106
- Heart Failure: A Practical Approach to Treatment by William Abraham on page 348
- The Statistical Analysis of Failure Time Data (Wiley Series in Probability and Statistics) by John D. Kalbfleisch on page 342
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