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The Art of Genes: How Organisms Make Themselves [Hardcover]

Enrico Coen (Author)
4.3 out of 5 stars  See all reviews (10 customer reviews)


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Book Description

0198503431 978-0198503439 July 15, 1999 1

Over the past twenty years there has been a revolution in biology--for the first time scientists have been able to unravel the details of how organisms make themselves. The mechanisms by which a fertilized egg develops into an adult can now be grasped in a way that was unimaginable a few decades ago. The Art of Genes is the first account of these exciting new findings, and of their broader significance in how we view ourselves.
Through a highly original synthesis of sciece and art, Enrico Coen vividly describes this revolution in our understanding of how plants and animals develop. Drawing on a wide range of material--from flowers growing petals instead of sex organs, and flies that develop an extra pair of wings, to works of art by Leonardo and Magritte--he explains in lively accessible prose the meaning of genes. Coen draws parallels between the way genes respond to the developing pattern of an organism and the way an artist responds to a painting being created on canvas, a memorable analogy that shows how the organism develops through an interactive dialogue in which there is no separation between plan and execution.
There have been many attempts to resolve the paradox of how organisms make themselves. Lucid, authoritative, and entertaining, The Art of Genes offers fresh and exciting insights into the nature of evolution, development, and human creativity.

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Editorial Reviews

Review

`'...(One of the book's great merits is Coen's sense of the history of his subject,...I am delighted that one of the leading practitioners in the field should have taken time off from the lab to tell the rest of us what is going on...there is nothing here you cannot understand if you want to...I would have loved this book at 16, and so should anyone-aged 16 60 60- who really wants to understand development.'' John Maynard Smith, Nature Vol.398, 25 March 1999.

'I hope it is widely read and discussed'. interdisciplinary Science Reviews, 1999, Vol. 24, No. 3

'..the book arrives at fresh and exciting insights into the nature of evolution,development and human creativity..' Ethology Ecology and Evolution

About the Author


Enrico Coen is Professor in the Genetics Department at the John Innes Centre, Norwich.

Product Details

  • Hardcover: 386 pages
  • Publisher: Oxford University Press, USA; 1 edition (July 15, 1999)
  • Language: English
  • ISBN-10: 0198503431
  • ISBN-13: 978-0198503439
  • Product Dimensions: 9.2 x 6.4 x 1.2 inches
  • Shipping Weight: 1.8 pounds
  • Average Customer Review: 4.3 out of 5 stars  See all reviews (10 customer reviews)
  • Amazon Best Sellers Rank: #2,742,379 in Books (See Top 100 in Books)

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Customer Reviews

10 Reviews
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3 star:
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Average Customer Review
4.3 out of 5 stars (10 customer reviews)
 
 
 
 
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15 of 15 people found the following review helpful:
5.0 out of 5 stars The Art of Explaining, July 16, 2000
By 
G. Korthof (The Netherlands) - See all my reviews
(REAL NAME)   
This review is from: The Art of Genes: How Organisms Make Themselves (Hardcover)
I always had the feeling that evolution was the inventor of new things and development was a secondary problem of how to build an organism from information already present in the fertilised egg. Now I know what problems need to be solved in building a multicellular organism from a single cell in the first place. Enrico Coen magnificently explains how the head-tail, ventral-dorsal, left-right and inside-outside axis is build out of nearly nothing. The subtitle of the book is a perfect illustration of the task: How organisms make themselves (without help from outside). The problem looked only harder since the discovery of DNA : the information in DNA is one-dimensional, so how to build a 3-dimensional organism on the basis of that? No wonder that people in previous centuries saw miniature humans in egg or sperm. But since that 'solution' was refuted, the problem confronted us again: how do organisms make themselves? Enrico Coen gives deep insights with the help of metaphors derived from art and with the necessary scientific details and without confusing us with too many complexities. Coen explains the crucial role of genes without being a genetic reductionist. His examples are both from animals and plants, wich I find an advantage. This book is an achievement. The only criticism I have is that the main metaphor Coen uses is about colors and all the illustrations are in black-and-white! At least the hardback edition should have color illustrations!
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7 of 7 people found the following review helpful:
4.0 out of 5 stars An amazing gem, April 2, 2000
This review is from: The Art of Genes: How Organisms Make Themselves (Hardcover)
This small book does nothing short of explaining the details of developmental biology in such an approachable synthesis that it should be required reading for all biology majors and their professors. Coen's understanding of his subject is obvious, but his ability to convey it is the amazing gem of this book. Success achieved!
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4 of 4 people found the following review helpful:
5.0 out of 5 stars Wow! Read this one..., December 13, 2000
By 
Michael O'Kane (Pasadena, TX USA) - See all my reviews
I've read a number of popular books on genetics. If you really want to know how a gene's influence unfolds in your body, this is the definitive book to read. Nobody is better than Dr. Coen at explaining how genes work in colorful metaphors that the layperson can understand. He writes concise summaries at the end of every chapter (Why don't other popular science writers do that?) Highly recommended reading.
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There are many different ways of making things, from the highly mechanised and automatic, like the manufacture of a car, to the more open-ended and creative, as when a work of art is produced. Read the first page
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