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Asymmetric Catalysis on Industrial Scale: Challenges, Approaches and Solutions (Chemistry)
 
 
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Asymmetric Catalysis on Industrial Scale: Challenges, Approaches and Solutions (Chemistry) [Hardcover]

Hans Ulrich Blaser (Editor), Elke Schmidt (Editor)

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Book Description

January 2, 2004 Chemistry
Edited by two of the experts in the field, the central aim is to show organic chemists working in process development that enantioselective catalysis is suitable for the large-scale production of enantioenriched intermediates. In so doing, it is equally a source of information and inspiration for academic research, and, with its contribution by Noble prizewinner W. S. Knowles, will also heighten the status of industrial catalyst specialists working in the exciting field of enantioselective catalysis.
Some 25 contributions from top industrial researchers around the world present case studies on the development of the widest possible range of large-scale enantioselective processes, featuring stereoselective production processes of fine-chemicals, agrochemicals and pharmaceuticals. Clearly structured according to the nature of the task, this handbook adopts a problem-driven approach such that readers can easily find how colleagues have dealt with a similar situation.

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Editorial Reviews

Review

"I highly recommend this book to all organic chemists in industry and academia, but particularly those in development and production. Not only is it an excellent reference work, it is also a thumping good read!"

Peter Spargo, Organic Process Research & Development

"This book is a must for process developers, and is of interest to both chemists and biochemists...Moreover, the book is easy and relaxing to read, and the variety of topics invites browsing."

"Dieses Buch ist ein "Muss" für Prozessentwickler, wobei nicht nur Chemiker, sondern auch Biochemiker angesprochen sind...Daneben läßt sich das Buch auch "einfach so" gut lesen, die Vielfalt der Themen lädt geradezu zum Schmökern ein!"

Rainer Stürmer, BASF AG, Ludwigshafen
Angewandte Chemie + IE 20/04

From the Back Cover

Edited by two of the experts in the field, the central aim is to show organic chemists working in process development that enantioselective catalysis is suitable for the large-scale production of enantioenriched intermediates. In so doing, it is equally a source of information and inspiration for academic research, and, with its contribution by Nobel prizewinner W.S. Knowles, will also heighten the status of industrial catalyst specialists working in the exciting field of enantioselective catalysis.

Some 25 contributions from top industrial researchers around the world present case studies on the development of the widest possible range of large-scale enantioselective processes, featuring stereoselective production processes of fine-chemicals, agrochemicals and pharmaceuticals. Clearly structured according to the nature of the task, this handbook adopts a problem-driven approach such that readers can easily find how colleagues have dealt with a similar situation.


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Inside This Book (learn more)
First Sentence:
The development of catalysts for asymmetric hydrogenation began with the concept of replacing the triphenylphosphane ligand of the Wilkinson catalyst with a chiral ligand. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
candoxatril precursor, racemic epichlorohydrin, microbial resolution, assimilating bacterium, racemization conditions, ethyl hydrocinnamate, imine hydrogenation, asymmetric transfer hydrogenation, phosphane oxide, titrating agent, chiral cyanohydrins, chiral switch, biocatalytic steps, substrate purity, biocatalytic process, asymmetric bias, enantioselective hydrogenation, asymmetric catalysis, secondary alcohol dehydrogenase, asymmetric hydrogenation, biocatalytic approaches, biocatalytic synthesis, enzymatic resolution, biocatalytic production, cyanohydrin formation
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Tetrahedron Lett, New York, Schmidt Copyright, Tetrahedron Asymmetry, Marcel Dekker, Academic Press, Chem Soc, Process Res, Catalytic Asymmetric Synthesis, Dicalite Speedex, John Wiley, Patent Appl, Platelet Glycoprotein, Pure Appl, Hoffmann-La Roche, Angew Chem, Asymmetric Biocatalysis, Comparison of Routes, Perkin Trans, Catalysis of Organic Reactions, Drug Discov, Incubation Period, Novo Nordisk, Optimization of Reaction Conditions, Solvay Enzymes
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