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Autism's False Prophets: Bad Science, Risky Medicine, and the Search for a Cure [Paperback]

Paul A. Offit
4.3 out of 5 stars  See all reviews (127 customer reviews)

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Book Description

March 29, 2010

A London researcher was the first to assert that the combination measles-mumps-rubella vaccine known as MMR caused autism in children. Following this "discovery," a handful of parents declared that a mercury-containing preservative in several vaccines was responsible for the disease. If mercury caused autism, they reasoned, eliminating it from a child's system should treat the disorder. Consequently, a number of untested alternative therapies arose, and, most tragically, in one such treatment, a doctor injected a five-year-old autistic boy with a chemical in an effort to cleanse him of mercury, which stopped his heart instead.

Children with autism have been placed on stringent diets, subjected to high-temperature saunas, bathed in magnetic clay, asked to swallow digestive enzymes and activated charcoal, and injected with various combinations of vitamins, minerals, and acids. Instead of helping, these therapies can hurt those who are most vulnerable, and particularly in the case of autism, they undermine childhood vaccination programs that have saved millions of lives. An overwhelming body of scientific evidence clearly shows that childhood vaccines are safe and does not cause autism. Yet widespread fear of vaccines on the part of parents persists.

In this book, Paul A. Offit, a national expert on vaccines, challenges the modern-day false prophets who have so egregiously misled the public and exposes the opportunism of the lawyers, journalists, celebrities, and politicians who support them. Offit recounts the history of autism research and the exploitation of this tragic condition by advocates and zealots. He considers the manipulation of science in the popular media and the courtroom, and he explores why society is susceptible to the bad science and risky therapies put forward by many antivaccination activists.


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Autism's False Prophets: Bad Science, Risky Medicine, and the Search for a Cure + Deadly Choices: How the Anti-Vaccine Movement Threatens Us All + Vaccines and Your Child: Separating Fact from Fiction
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Editorial Reviews

From Publishers Weekly

Attempting to answer the enormous frustration and unhappiness of parents "tired of watching their autistic children improve at rates so slow it's hard to tell if they are improving at all," pediatrics professor and vaccine researcher Offit explores purported causes and cures. Examining false approaches like facilitated communication ("a massive, nationwide delusion") and secretin injections ("no better than salt water"), and mistaken theories of origin (the MMR vaccine, thimerosol), Offit pleads with journalists to resist the lure of "dramatic headlines, advertising dollars, and ratings" rather than report an unconfirmed or untrustworthy study. The only worthwhile studies, Offit purports, are those meeting three criteria: "transparency of the funding source, internal consistency of the data, and reproducibility of the findings." Overall, Offit's text seems unbalanced: though he takes on the "$40-billion-a-year" alternative medicine industry, he's largely silent on the much larger pharmaceutical industry; and after 10 chapters of debunking the "false prophets," there's just one brief chapter on what is known about autism causes and cures. A thorough and convincing debunker, however, Offit will likely leave parents still hunting for information, albeit better armed to find it.
Copyright © Reed Business Information, a division of Reed Elsevier Inc. All rights reserved. --This text refers to the Hardcover edition.

Review

Every child has a right to be vaccinated against deadly diseases. We started Every Child By Two to protect children from diseases. It didn't occur to me that I would also have to protect them from misinformation about life-saving vaccines. Paul A. Offit's book sets the facts straight.

(Rosalynn Carter, former first lady, cofounder of Every Child By Two)

Autism's False Prophets is a compelling story of heartbroken parents, understandably desperate for an explanation of autism, being taken in by false hopes unsupported by genuine science. This book goes to the heart of a question that affects every aspect of American culture and political life. Are public policies to be determined by evidence and reason or by emotions that, however intense they may be, have nothing to do with reality?

(Susan Jacoby, author of The Age of American Unreason)

A definitive analysis of a dangerous and unnecessary controversy that has put the lives of children at risk. Paul A. Offit shows how bad science can take hold of the public consciousness and lead to personal decisions that endanger the health of small children. Every parent who has doubts about the wisdom of vaccinating their kids should read this book.

(Peter C. Doherty, Ph.D., St. Jude's Children's Research Hospital and Nobel Laureate in Medicine for fundamental contributions in Immunology)

In his latest book Paul A. Offit unfolds the story of autism, infectious diseases, and immunization that has captivated our attention for the last decade. His lively account explores the intersection of science, special interests, and personal courage. It is provocative reading for anyone whose life has been touched by the challenge of autism spectrum disorders.

(Susan K. Klein, MD, Ph.D., Case Western Reserve Hospital, and Rainbow Babies and Children's Hospital, Case Medical Center)

[A] thoughtful and readable study.

(Library Journal (starred review))

Enlightening, highly readable and... timely.

(Rahul K. Parikh, M.D. Salon.com)

Arguably the most courageous and most knowledgeable scientist about vaccines in the United States.

(Robert Goldberg New York Post)

[Dr. Offit] has done a huge public service by exposing the tragic and dangerous place the anti-vaccine hysteria has taken us.

(Huntly Collins Philadelphia Inquirer)

An invaluable chronicle that relates some of the many ways in which the vulnerabilities of anxious parents have been exploited.

(Linda Seebach Wall Street Journal)

A good read and an important piece of work.

(Lisa Jo Rudy About.com)

More than a book about a disease, it is an ode to uncorrupted science and a cautionary tale that data alone is never enough.

(SEED magazine 1900-01-00)

[Offit] provides important insight into the fatal flaws of the key arguments of vaccine alarmists.

(Buffalo News)

A very good read.

(Dom Giordano The Bulletin)

A sobering indictment.

(Isabelle Rapin, M.D. Neurology Today)

Highly recommended.

(Choice)

A fascinating read... Eloquently and clearly written.

(Stan L. Block, MD Infectious Diseases in Children)

A very helpful book for both medical personnel and parents.

(The New England Journal of Medicine)

The book is a fantastic read. I recommend it to all physicians and their patients and families.

(Brian Alverson, MD Archives of Pediatric & Adolescent Medicine)

This is a powerful book which should be read by all professionals working in the area ofmedicine.

(Michael Fitzgerald Social History of Medicine 1900-01-00)

Paul A. Offit is one of the most respected scientists and clinicians in a field of vital importance to public health.

(Patricia M. Rodier BioScience)

[This] book doesn't just show that the anti-vaccine activists are wrong; it attempts to explain why, in our culture, they tend to win.

(Jason Fagone Philadelphia Magazine)

Detailed but easily readable... should be required reading for any parents who are considering denying vaccination to their children.

(Communication: The Magazine of the National Autistic Society 1900-01-00)

Arguably the most detailed and thorough history available of the current anti-vaccine movement.

(Roy Richard Grinker Journal of Autism and Developmental Disorders 1900-01-00)

[A] must-read... it will keep pediatricians and pediatric neurologists awake over the nightmarish possibilities of pseudoscience in the 21st century.

(Roger A. Brumback, M.D. Journal of Child Neurology 1900-01-00)

The vast range of professionals who may be enriched, professionally, by the book's contents extends to: psychologists, psychiatrists, neurologists, neuroscientists, speech pathologists, pediatricians, primary care physicians, geneticists, virologists, immunologists, vaccine experts, nurses, infectious disease experts, internists, gastroenterologists, epidemiologists, public health professionals, special education teachers, bioethicists, biochemists, biologists, biostatisticians, endocrinologists, pharmacists, pharmacologists, pharmaceutical industry professionals, health policy makers, journalists, politicians, and trial lawyers.

(Leo Uzych Metapsychology)

Seeking to help readers realize the truth about Autism, Autism's False Prophets is a much need read, not to be missed.

(Midwest Book Review 1900-01-00)

Product Details

  • Paperback: 328 pages
  • Publisher: Columbia University Press; 1 edition (March 29, 2010)
  • Language: English
  • ISBN-10: 023114637X
  • ISBN-13: 978-0231146371
  • Product Dimensions: 6 x 0.7 x 9 inches
  • Shipping Weight: 15.2 ounces (View shipping rates and policies)
  • Average Customer Review: 4.3 out of 5 stars  See all reviews (127 customer reviews)
  • Amazon Best Sellers Rank: #15,840 in Books (See Top 100 in Books)

More About the Author

Paul A. Offit, M.D., is Chief of the Division of Infectious Diseases and Director of the Vaccine Education Center at the Children's Hospital of Philadelphia, as well as the Maurice R. Hilleman Professor of Vaccinology and Professor of Pediatrics at the University of Pennsylvania School of Medicine. An expert in the field of vaccines, he is a recipient of many awards, including the J. Edmund Bradley Prize for Excellence in Pediatrics from the University of Maryland Medical School; the Young Investigator Award in Vaccine Development from the Infectious Disease Society of America; and a Research Career Development Award from the National Institutes of Health. His books include the recent Autism's False Prophets: Bad Science, Risky Medicine, and the Search for a Cure. Visit his website at www.paul-offit.com.

Customer Reviews

This book is very well written. Anna Przyjemska  |  43 reviewers made a similar statement
Ms. McCarthy has a child with autism and she is convinced that a vaccine caused her child's autism. David C. Brayton  |  20 reviewers made a similar statement
Dr. Offit describes the poor job the media do of covering science stories. E. Gross  |  10 reviewers made a similar statement
Most Helpful Customer Reviews
242 of 297 people found the following review helpful
5.0 out of 5 stars "Please don't read it" - say anti-vaxers September 18, 2008
Format:Hardcover
If you look at all the negative reviews of this book so far, you won't find any indications that the reviewers have actually read the book. You will also note they urge readers not to buy the book. Once you read the book, you'll understand why.

Despite what others have said, the book didn't read like a "smear-fest." The closest it comes to that is the use of the word "quackery" in one place. What Dr. Offit has done is provide a well-referenced historical account of the activities of a sub-group of the autism community in the last decade.

If you are someone who tries to keep reasonably up to date with the political going-ons of the autism world, you might be thinking, "I won't learn much from this book." But you'd be wrong. There are many interesting tidbits of information you probably haven't heard of before; such as David Kirby's interaction with Curtis Allen of the CDC (page 151). There's also a lengthy discussion of the meetings and thinking that led to the decision to remove thimerosal from pediatric vaccines.

Perhaps there is some information the book is missing. For example, you won't find a discussion of Dan Olmsted's negligence in his Amish reporting. More could've been said of JB Handley's bullying tactics and his failed prophecies ("autistic children will be cured within 2 years"). There's no mention of John Best, a fringe but prominent member of the anti-vax movement.

This is understandable, though. A book is insufficient to air all the dirty laundry of the anti-vaxers. You'd need a whole encyclopedia for that.
Was this review helpful to you?
242 of 298 people found the following review helpful
5.0 out of 5 stars An Important Book September 30, 2008
Format:Hardcover
I just read an article about Jenny McCarthy--yes, that Jenny McCarthy. Ms. McCarthy has a child with autism and she is convinced that a vaccine caused her child's autism. She now considers herself an expert because she attended the "University of Google" (her words, not mine) and that she is right because "because there is an angry mob on my side" and "until [someone] walks in our shoes, [he/she] really has no idea."

That's right...because there is an angry mob on her side, the consensus of scientists that attended real schools and obtained real master and doctorate degrees in things like epidemiology and medicine, is wrong.

Dr. Offit faces a very challenging opponent and he did it with an exceptionally calm and rationale analysis of vaccines, why they are safe and more importantly, why the quacks and anti-vaxxers are wrong. And he did it in a style that is very readable by the lay person.

When Dr. Offit starts laying out damning facts against the anti-vaxxers, you will be left agape. For example, Dr. Wakefield took $800,000 from a plaintiff's attorney and used it to fund his studies and never disclosed where the funding came from, he never obtained informed consent and when he ran his studies past IRBs, they were anything but medically qualified. Just astounding. Of course, the results of his studies have never been duplicated and any physiological basis for his hypothesis has been debunked.

Yet, there are people who flock to Dr. Wakefield and give him lots of money for unproven and dubious-at-best treatments and cures. Very, very sad.

Dr. Offit also discusses how science is perceived in society. A lot of people simply don't "believe in" science and how science is done. Dr. Offit analyzes this later in the book and it is hardly comforting.
... Read more ›
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95 of 116 people found the following review helpful
5.0 out of 5 stars Autism Quackery Unmasked September 21, 2008
Format:Hardcover
Dr. Offit presents shocking details about the people and organizations who have been trying to scare parents into not immunizing their children. I was startled by the amount of money lawyers paid to doctors and other scientists who were willing testify in court that vaccines cause autism. Parents who are frightened about immunization should find this book reassuring.
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149 of 184 people found the following review helpful
5.0 out of 5 stars Excellent book! September 22, 2008
Format:Hardcover
Fascinating and readable. "Autism's False Prophets" traces the histories of the MMR-autism and thimerosal-autism controversies, and discusses the science in clear, layman's language. I found the book very difficult to put down: it's a wonderful (and enlightening) read for anyone interested in autism, vaccines, or scientific controversy, and its "Science and Society" chapter should be required reading for any parent (or any person) researching vaccines or other medical decisions.
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50 of 62 people found the following review helpful
5.0 out of 5 stars Excellent. Totally Recommended September 25, 2008
By Chinari
Format:Hardcover
Accurate, historic events. Well written. If you have questions in your mind about this topic, READ IT!!!.
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67 of 85 people found the following review helpful
5.0 out of 5 stars A fascinating, thought-provoking read September 26, 2008
By Dawn
Format:Hardcover
I really enjoyed reading this book. It is very hard to put down. Although I have read a lot about autism, I didn't know a lot of the information Dr. Offit included in his book. As a physician-researcher, he has clearly done his homework (unlike a referenced journalist who did NOT do his, especially among the Amish). I have an extra copy that I am going to donate to our library, to make sure they have one for all to read.
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55 of 71 people found the following review helpful
5.0 out of 5 stars A Very Important Book October 6, 2008
By billdar
Format:Hardcover|Amazon Verified Purchase
Paul Offit's writings and his behavior have consistently reflected his strong commitment to both children's health and to science. This book underscores the many problems that can occur when emotion-driven rather than science-driven actions impact: treatments, resource allocations, policies, and ultimately health outcomes. "Autism's False Prophets" is well written and I couldn't put it down. Recognizing that Dr. Offit is donating all royalties from the sale of this book to autism research, I just ordered four more copies to give to friends.
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Most Recent Customer Reviews
5.0 out of 5 stars Trust Dr. Offit over Jenny
A riveting, at times heartbreaking, book that seeks to refute the widespread belief that childhood vaccines cause autism. Read more
Published 10 days ago by SKB
5.0 out of 5 stars An excellent book in every way
This is the best book I've read about vaccine controversies and the debates surrounding autism by pretty much any criterion I can think of. Read more
Published 12 days ago by Dorit Rubinstein
5.0 out of 5 stars A Necessary Addition to Any Collection on this Subject
Dr. Offit takes the reader through a detailed look at one of the most important subjects of our time: autism. Read more
Published 1 month ago by S. Herlihy
1.0 out of 5 stars An uncaring money making non-science book.
Paul Offit is so certain that vaccines are safe and in particular the MMR vaccine and yet he's not undertaken ANY research into why Autism now affects 1 in 50. Read more
Published 2 months ago by Binny Yorkminster
4.0 out of 5 stars Autism's False Prohets: Bad Science, Risky Medicine, and the Search...
I have a five year old granddaughter that is very high on the autism spectrum and I needed to read about what can and what cannot be the cause of her autism.
Published 5 months ago by Terry Dunham
4.0 out of 5 stars A good read
A well written book offering a comprehensive retrospective look on the autism/MMR/mercury vaccine controversy. A good read for anyone who is interested in this topic.
Published 5 months ago by ht
1.0 out of 5 stars Thanks for the pig virus
Anything produced by Dr. Offit is a fraud as far as I'm concerned. To me, he is a doctor that is just interested in money. Read more
Published 5 months ago by Sammy A.
5.0 out of 5 stars Excellent and highly readable
This book documents the detours and roadblocks thrown up against progress in autism research by a loud and politically connected minority, who've decided despite massive evidence... Read more
Published 5 months ago by Andrew King
5.0 out of 5 stars A book of courage which names names
I read this book after touring the Marcus Autism Center in Atlanta, a National Center of Autism. You will not read this book and emerge with a good feeling about human nature, as... Read more
Published 6 months ago by JanisLG
1.0 out of 5 stars Biased
While this book does show the errors committed by greedy researchers in the early anti-vaccination movement, it does not address the other issues revolving around the current... Read more
Published 6 months ago by Christopher Kennedy, MD
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Amazon.com: Why are people who have **not read the book** "reviewing" it?
C. Clark is a mom of a child in the autism spectrum. If you didn't know that, it means you're out of touch with the autism community, and you also didn't read the book! Either way, how does that matter? It's ridiculous to suggest that only parents can have opinions about matters that potentially... Read more
Sep 29, 2008 by Joseph S. |  See all 8 posts
Evidence-based medicine saves lives
I don't know about kicking their dogs, but I do think it's an interesting psychological phenomenon - that people get so attached to a belief they like, they'll cling to it even as the evidence against it becomes overwhelming. It's just too bad that in the case of autism, the consequences fall on... Read more
Aug 30, 2008 by wisarc |  See all 6 posts
paul offit makes money on vaccines- can you really trust him for the truth?
JGC, I don't know if you know this, but posting something more than once doesn't make it true.

The calculation showing that an infant can easily tolerate an antigenic challenge equal to as many as 100,000 vaccines is substantiated in the scientific literature. If you want to challenge it,... Read more
Aug 7, 2008 by wisarc |  See all 33 posts
Why have some reviews been deleted?
that's actually not true -- unfavorable reviews were deleted as well
Sep 16, 2008 by K. Rosenberg |  See all 2 posts
Paul Offit is afraid of honest science
Basic reading, M. Morrison.

"On the basis of data from areas of environmental contamination, in 1997, the EPA revised its mercury intake guidelines; it is now the most conservative guideline, and is one fourth the intake guidelines of the Food and Drug Administration (FDA). Five points... Read more
Aug 24, 2008 by wisarc |  See all 6 posts
Does this book discuss behavior-modifica... and aversives therapy? Be the first to reply
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