Modern biology is increasingly focused on the role of repetitive anatomical structures in the embryological construction of organisms. The discovery of the homeobox (Hox) genes by Edward Lewis in 1978 ushered in a series of stunning revelations such as the fundamental commonality of insect segments and mammalian vertebrae - a wild and ridiculed idea first proposed by Etienne Geoffroy Saint-Hilaire in 1822 that has now been proven correct. Axial Character Seriation in Mammals is an unabridged edition of the 1986 Harvard University PhD Thesis of Aaron G. Filler, MD, PhD that pioneered our modern reassessment of mammalian vertebrae in the light of the new homeotic biology. As Dr. Filler points out in fascinating detail, the leading explanations of similarity among animals before Darwin were arrayed around the vertebrae of the spine in works by Sir Richard Owen, Johann Wolfgang Goethe and Geoffroy Saint-Hilaire. This was the theoretical structure that was overturned and demolished by Darwin's ideas about similarity due to common descent. In a stunning reversal, modern homeotic genetics has shown that repeating structures are indeed critical to understanding animal similarity. This work is the first study of the modern era that views vertebrae as a key to unlocking the way in which Nature has organized repeating biological structures. For the 150 years since the Great Academy Debate of 1830 appeared to demolish Geoffroy Saint-Hilaire's ideas, vertebrae have been seen as no more than some bones in Vertebrate animals that are involved in support and locomotion. Axial Character Seriation in Mammals, however, explores the fascinating traces of how the morphogenetic genes sculpt and organize serially repeating structures, thus re-establishing the vertebrae as a legitimate and compelling subject of modern science.
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About the Author
Aaron Filler is one of the world's leading experts in nerve and spinal diagnostics and surgery. A Medical Director at the Cedars Sinai Institute for Spinal Disorders, he pioneered the field of MR nerve imaging or MR Neurography and advanced MRI guided surgery. He has numerous patents and publications in a variety of medical and biological fields. He is the author of Do You Really Need Back Surgery from Oxford University Press.
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vertebral processes, articular morphology, secondary articulations, axial function, lateral process, axial motion, field homology, articular series, diaphragmatic vertebra, planar pitching, dorsal cylinder, cylindrical articulations, tubercular articulation, first lumbar transverse process, serial anatomy, more posterior vertebrae, third tubercle, capitular articulation, thoracic transverse process, sequential shaping, lumbar transverse processes, serial homolog, mammalian vertebrae, homeotic change, anticlinal vertebra Key Phrases - Capitalized Phrases (CAPs): (learn more)
Seriational Plasticity, Hominoid Transverse Processes, Van Valen, Axial Articular Series, Heterochronic Propagation, Structure of Lumbar Transverse Processes, Amniote Diarthra, Abandoning the Homology Paradigm, Vertebral Processses, Genetic Disruptions of Axial Morphogenesis, Diaphragmatic Joints, Specialized Axial Processes, Hominoid Morphs, Morphology of the Laminapophysis, Setting of Serial Transformation, The Nature of Homeotic Change, Replication of Primary Articular Surfaces, Museum of Comparative Zoology, Articular Constraints, Osteology of the Mammalia, Origin of Species, Harvard Peabody, Great Anteater, Axial Morphogenesis Browse Sample Pages:
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vertebral processes, articular morphology, secondary articulations, axial function, lateral process, axial motion, field homology, articular series, diaphragmatic vertebra, planar pitching, dorsal cylinder, cylindrical articulations, tubercular articulation, first lumbar transverse process, serial anatomy, more posterior vertebrae, third tubercle, capitular articulation, thoracic transverse process, sequential shaping, lumbar transverse processes, serial homolog, mammalian vertebrae, homeotic change, anticlinal vertebra Key Phrases - Capitalized Phrases (CAPs): (learn more)
Seriational Plasticity, Hominoid Transverse Processes, Van Valen, Axial Articular Series, Heterochronic Propagation, Structure of Lumbar Transverse Processes, Amniote Diarthra, Abandoning the Homology Paradigm, Vertebral Processses, Genetic Disruptions of Axial Morphogenesis, Diaphragmatic Joints, Specialized Axial Processes, Hominoid Morphs, Morphology of the Laminapophysis, Setting of Serial Transformation, The Nature of Homeotic Change, Replication of Primary Articular Surfaces, Museum of Comparative Zoology, Articular Constraints, Osteology of the Mammalia, Origin of Species, Harvard Peabody, Great Anteater, Axial Morphogenesis Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Surprise Me!
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