depends on the integration. it should be as easy as any other tv. It will take an infrared send to control the tv inputs, it has enough ins/outs to handle hdmi sources as well as composite and component. I have had no issues with automating a harmony remote with it.
Coaxial will only support standard definition 480i quality video. If you want to use the full potential of this TV, HDMI is always the way to go. If you're cable set top box does not support HDMI, I would recommend upgrading. It's not gonna cost that much more. In any case, always try to use HDMI to get the most out of any HDTV. Just a heads up, when using HDMI, you can still receive standard definition channels that only go to 480i but with having this cable and an HD source, you are capable of getting 1080i at 24 frames per second (not sure if they actually broadcast in 1080p...).