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Basic Neurochemistry: Molecular, Cellular, and Medical Aspects (Periodicals) Hardcover – November 6, 1998

3 customer reviews
ISBN-13: 978-0397518203 ISBN-10: 039751820X Edition: 6th

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Product Details

  • Series: Periodicals
  • Hardcover: 1200 pages
  • Publisher: Lippincott Williams & Wilkins; 6th edition (November 6, 1998)
  • Language: English
  • ISBN-10: 039751820X
  • ISBN-13: 978-0397518203
  • Product Dimensions: 2.2 x 10 x 7.5 inches
  • Shipping Weight: 5.2 pounds
  • Average Customer Review: 4.7 out of 5 stars  See all reviews (3 customer reviews)
  • Amazon Best Sellers Rank: #839,851 in Books (See Top 100 in Books)

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13 of 13 people found the following review helpful By Math PC on September 18, 2001
Format: CD-ROM
This book is ideal for both undergrad and grad students in the fields of neuroscience, pharmacology, and psychology. The information is arranged neatly with the authors introducing concepts at the cellular level (anatomy, physiology, and biochemistry), then moving on to intercellular signaling. From here, the neurochemical factors are introduced, outlining their functional significance at the molecular level. The last few chapters of this book expands on the role of several neurochemical interactions in the context of diseases like Alzheimer's and Creutzfeld-Jakob (Mad cow-like disorder), Huntington's (and other related basal ganglia disorders), and several Psychiatric disorders (anxiety, mood disorders, addiction, etc). The figures are excellent, and succintly explained. Several color plates are also included. Note that the book I bought has textual addenda/errata located at the back, in order to correct factual/typographical errors. Nevertheless, these corrections don't affect the whole integrity of the contents, but rather they strengthened it.

This book also includes a CD-ROM which constitutes the book's contents, and provides nice figures that you can use as a reference. Overall, I recommend this book if you think you will embark on a career in the medical sciences, or if you are an undergrad that would like to go to grad schools.
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8 of 9 people found the following review helpful By A Customer on June 21, 2000
Format: Hardcover
The topics in the book are arranged well. It is suitable for both junior and senior students. The concepts are explained clearly. This must be the most excellent book in this field for introductory courses.
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9 of 26 people found the following review helpful By A Customer on March 11, 2001
Format: Hardcover
Some fresh angles on the memory problem can be pieced together from distinct bits and pieces included in this book on the brain's catabolic habits, on starvation and diabetes, and on the effects of alcohol and other drugs on the chemistry of the brain.
Alcoholism offers us clues to how the memory works and fails. In both chronic and acute alcoholism, it appears the pen of memory stops writing quite suddenly. In the extreme chronic condition, an alcoholic who has progressed to Wernicke-Korsakoff's syndrome can be trapped forever in a particular day - the day the pen of memory lifted.
For a few fortunate alcoholics the brain's working memory can be restored with early injections of Vitamin B1, which is thiamine. Thiamine is a very common co-factor. It operates in a great many different biochemical pathways. But look: One among those many pathways is quite possibly the biochemical pathway that is essential for -- and could thus lead us straight to -- the human memory machine. The grand prize. This helpful hint has never been followed up exhaustively, although there are lots of takes on what might be going on.
This book holds a second hint. Perhaps the same crucial biochemical pathway to memory can be interrupted at a different point, in a different way -temporarily -- in the brain of a drinker experiencing an acute alcoholic memory blackout. See pages 659-660 for a summary discussion of ethanol, glucose and ketone body catabolism in the brain.
Notice sometime, in the spirit of science, the horrible, noxious, acetone like odor on the breath of a heavy drinker. It is very evident on the morning after. Ketone bodies are still so plentiful in the blood that an observer can smell them, and the brain (perhaps thinking the body is starving) may have shifted gears to protect itself.
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