“I could recommend Rosenbaum’s book for pharmacology students because it is written from a perspective of drug action . . . Overall, this is a well-written introduction to PK/PD that may fill a small niche in a well-served market. “ (British Toxicology Society Newsletter, 1 June 2012)
"In summary, I believe that this book is successful in what it sets out to do. For those readers who are interested in getting to grips with the basics of the time course of onset, offset and extent of drug effects then this is the book for you. I am certainly recommending this book for my graduate students." (British Journal of Clinical Pharmacology, 2011)
"A readable font size, good quality paper and a stout binding make this an excellent offering ... This is an ideal textbook for those starting out on the pharmacokinetic trail and also for use as a reference book for those who delve occasionally into this subject." (International Society for the Study of Xenobiotics, 1 April 2012)
"In short, this is a thorough and well-designed presentation and development of key concepts in pharmacokinetics and pharmacodynamics. It is a very useful textbook, and one that I would be comfortable using in both medical and graduate teaching." (Doody's, 21 October 2011)
"Unlike other basic textbooks that cover only pharmacokinetics, the author has done justice to the title of the book by covering pharmacodynamics. Pharmacodynamics is covered in greater depth than other books in the same category. What makes the book to stand out is that the author has nicely blended the concepts of receptor theory from classical pharmacology with the modern science of PK/PD.... The book truly helps readers to understand the science of pharmacokinetics and drug action. The Excel-based simulation exercises incorporated into the text helps the reader to put his/her learning into practice, albeit in a virtual environment.... The book is strongly recommended for use in undergraduate studies of PK/PD, and by those in drug research interested in having a basic understanding of the science of PK/PD."
, PhD, Anoixis Corporation
"Sara Rosenbaum's book is a thoroughly modern approach to pharmacokinetics and pharmacodynamics. It is well written and well thought out – a blend of pharmacokinetic-pharmacodynamic theory and modeling/analysis concepts. The pharmacodynamic models are up to date with recent advances in the field, such as tolerance, indirect, and basic disease progression models, being presented. The web page simulations were fun to play around with allowing the user to change the model parameters and see how the results change. Rather than being a dry subject with just endless equations, the connection between the web-based simulations and the book allows the reader to be engaged and understand the subject with greater ease."
—Peter L. Bonate, PhD, author of Pharmacokinetic-Pharmacodynamic Modeling and Simulation