Departing from O'Reilly's earlier monograph Developing Bioinformatic Computer Skills, Tisdall's text is organized aggressively along didactic lines. Nearly all of the 13 chapters begin with twin bullet lists of Perl programming tools and the bioinformatic methods that require them. Likewise, the chapters end with exercises. String concatenation is illustrated with gene splicing, and regular expressions are taught with gene transcription and motif searching.
Tisdall emphasizes sequence examples throughout, leading up to an introduction to a Perl interface for the NIH GenBank biological database and the widely used BLAST sequence alignment tool. After a brief discussion of three-dimensional protein structure, he returns to sequence extraction and secondary structure prediction.
Tisdall's goal is to boost the beginning programmer into a domain of self-learning. He imparts essential etiquette for the success of programming newbies: use the wealth or resources available, from user documentation to Web site surveys to FAQs to How-To's to news groups and finally to direct personal appeals for help from a senior colleague. A well-plugged-in bioinformatics Perl student will soon discover Bioperl, an open-source effort to bring research-grade bioinformatic tools to the Perl community. Bioperl is described briefly at the end of Tisdall's book and will reportedly be a forthcoming title of its own in the O'Reilly bioinformatics series.
Although he introduces bioinformatics as an academic discipline, Tisdall treats it as a trade throughout his book. He indicates that open questions and computational hard problems exist, but does not describe what they are or how they are being tackled. Ultimately, Tisdall presents bioinformatics as another arrow in a bench scientist's quiver, very much like HPLC, 2D-PAGE, and the various spectroscopies.
As odd as a "bioinformatics-as-tool" book may be to its research proponents, the reduction of bioinformatics to trade status both deflates and vindicates the years of research, as Tisdall's work attests. --Peter Leopold
Comming from a biology background I found the layout of the book and the clear explainations very helpful.
I would recommend this book highly to anyone wanting to/needing to use Perl to handle their biological programming needs.
If you are new to perl and searching for a book that will help you learn perl from scratch, then look no more.
I bought this book knowing nothing about Perl. I'm not sorry I bought it, but it didn't get me very far. Read morePublished 10 days ago by DE
This book is a perfect learning package. If you are new to perl and searching for a book that will help you learn perl from scratch, then look no more. Read morePublished 10 months ago by GAYATHRI SURESH
I had somewhat mixed feeling about this book. To begin with I am a biologist with some background in programing. I do not think that this book can satisfy any of my needs. Read morePublished 12 months ago by Oleg Agafonov
Teaches basic scripting for managing bioinformatic data. Gave poor examples and explanations for the topics being discussed. I do not recommend this book.Published 12 months ago by MJR
i have study and apply information and Bioinformatic perls is very informative straight to the point well put together must get for basicPublished 21 months ago by William Savigne
This book is only good as a second reference for a beginner. I spent far too much time debugging scripts that probably worked in 2001. Read morePublished on July 15, 2012 by Kimist
This is not the first time I order books from Amazon. It only takes couple days to arrive. The book is used but it looks new! I really like Amazon!Published on October 8, 2011 by snowman
I have a MS degree in Bioinformatics and I bought this book to help me learn Perl for my job. During my training at the University, I wasn't taught Perl, because most programs... Read morePublished on July 15, 2011 by SB
I bought this book to create a working knowledge of programming, especially in the light of bioinformatics (I'm a biology grad student). Read morePublished on November 8, 2010 by maneki neko