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5 of 6 people found the following review helpful:
5.0 out of 5 stars
Great book on non-linear dynamics of metabolic pathways,
This review is from: Biochemical Oscillations and Cellular Rhythms: The Molecular Bases of Periodic and Chaotic Behaviour (Paperback)
Albert Goldbeter wrote in the 70s the first articles with models on the oscillations that arise from positive feed-back regulation on metabolic pathways and since then much work has been done by him and other groups on the non-linear behavior of these systems.
This book has great chapters such as the one decribing the transitions the glycolytic pathway can suffer when some biological parameters are modified, varying from a steady-state metabolic flux to an oscillatory, complex or even chaotic one. The math is quite advanced and in order to fully understand the consequences withdrawn from the models the reader will need a good knowledge of calculus more specifically of systems of non-linear differential equations. In order to get full advantage of this book I would recommend fetching his early articles in pubmed with the numerical parameters for the equations as well as implementing these models in Matlab or Mathematica. |
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Biochemical Oscillations and Cellular Rhythms: The Molecular Bases of Periodic and Chaotic Behaviour by A. Goldbeter (Paperback - April 13, 1997)
$92.00 $75.32
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