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Biochemistry (3rd Edition) [Hardcover]

Christopher K. Mathews , Kensal E. van Holde , Kevin G. Ahern
4.0 out of 5 stars  See all reviews (13 customer reviews)

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Book Description

December 10, 1999 0805330666 978-0805330663 3
Biochemistry,Third Edition merges a classical organization and presentation with contemporary insight, information, and technology, to make modern biochemistry interesting and accessible to today's students. Thoroughly updated to include the latest information, perspectives, and experimental techniques, the text is now supported by integrated media resources designed by the co-author Kevin Ahern. Together, the text and media resources provide students and instructors with a doorway to the vast world of biochemistry that is continuously evolving and which greatly exceeds what could be covered in a conventional textbook alone. As in previous editions, the authors introduce nucleic acid structure early (to clarify presentations of protein structure and function), emphasize the experimental roots of biochemistry (past and present), continually emphasize the energy relationships in biochemistry, and take a stepwise approach to complex metabolic pathways. The result is a thorough grounding in biology at the atomic/molecular level. The explosive growth of biochemistry, molecular biology, and biotechnology makes this approach particularly relevant for today's life science students.

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Editorial Reviews

About the Author

Christopher K. Mathews is Distinguished Professor and Chairman of the Department of Biochemistry and Biophysics at Oregon State University. Dr. Mathews was an Eleanor Roosevelt International Cancer Fellow at the Karolinska Institute in Stockholm in 1984-85 and Tage Erlander Guest Professor at Stockholm University in 1994-95. He has published several books and more than 125 scientific papers dealing with molecular virology, metabolic regulation, nucleotide enzymology, and biochemical genetics.


K.E. van Holde is Distinguished Professor Emeritus of Biophysics and Biochemistry at Oregon State University. Dr. van Holde's major research interest is the structure of chromatin; his work resulted in theaward of an American Cancer Society Research Professorship in 1977 and hiselection to the National Academy of Sciences in 1989. He has received Guggenheim, NSF, and EMBO Fellowships and is the author of two books and more than 175 scientific papers.


Kevin Ahern is a Senior Instructor in the Department of Biochemistry and Biophysics at Oregon State University, where he pioneered the development of Web-based courses for teaching biochemistry. He is a contributing editor to Science magazine and a columnist for Genetic Engineering News. He has edited two books, Biotechnology Software Reports - Computer Applications for Molecular Biologists and The Biotechnology Software Directory, A Buyer's Guide, and is the founder of DaVinci Press Ink, a scientific software consulting firm. Dr. Ahern's teaching experience includes undergraduate and graduate biochemistry courses.



Product Details

  • Hardcover: 1200 pages
  • Publisher: Prentice Hall; 3 edition (December 10, 1999)
  • Language: English
  • ISBN-10: 0805330666
  • ISBN-13: 978-0805330663
  • Product Dimensions: 1.8 x 8.6 x 10.9 inches
  • Shipping Weight: 5.8 pounds (View shipping rates and policies)
  • Average Customer Review: 4.0 out of 5 stars  See all reviews (13 customer reviews)
  • Amazon Best Sellers Rank: #561,556 in Books (See Top 100 in Books)

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Customer Reviews

Most Helpful Customer Reviews
12 of 12 people found the following review helpful
5.0 out of 5 stars Easy to understand, clear and well organized October 27, 1999
By A Customer
Format:Hardcover
Biochemistry by Mathews and van Holde is one of the best texts for any biochemist's need. The authors discuss almost all of the subjects any biochemistry class ever comes across. The language presented throughout the text is simple, yet cover the fundamental concepts nicely. The questions and answers given at the end of each chapter are well prepared and extremely useful for test preparation. This text is suitable for both medical and pure science students. I would give two thumbs up for Dr. Mathews and van Holde and cannot wait to see the new edition coming up.
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12 of 13 people found the following review helpful
5.0 out of 5 stars great book! April 25, 2001
Format:Hardcover
I am a biochemistry major at the university of the philippines. i have several biochem books on my shelf and i just recently purchased a copy of the 2000 edition (i also have the 2nd ed). the book just keeps getting better. the book really helps a lot especially when the class lecture corresponds with how the book presents the subject matter. as a biochem major, i'd say this is a pretty good way to present biochem. it makes it seem easy and fun to read. you look at the pictures and read the caption and you learn the idea in a flash.
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13 of 17 people found the following review helpful
3.0 out of 5 stars These people all lie January 24, 2005
Format:Hardcover
This book isn't very good. The reading, I will grant, isn't too bad. Most of the time it's easy to follow, and sometimes it's confusing. However, the problem comes when you try to put it all to the test and do the problems at the end of the chapter. Not only does the book present problems that were not covered in the reading, but it doesn't explain the answers, either. It just gives them to you. I am forced to constantly ask a friend of mine if he knows how to get the answer they give, because the book gives no indication of how to arrive at it. It also withholds information; in one problem in chapter 5 the answer they give is only possible, ONLY possible, if chymotrypsin cleaves a protein at isoleucine (the book only gives leucine, not iso-). In the next problem, it is virtually the same thing, taking cleavage information and trying to put amino acids in the correct order. However, in this one, their answer insists that you NOT cleave at isoleucine. Otherwise you'd be wrong and wonder what you did. Of course, you'd get no explanation. If you have to get this book for a class, then fine. Good luck with the homework if you have to turn in the problems. But if you're getting it to further challenge yourself of your own accord, search around for some type of solutions manual first, because this book won't tell you how to get anything. It assumes you have a lot of background knowledge already, so I don't know where one reviewer got the notion that this is great for beginners...if you want a good book for beginners, seek out the Garrett & Grisham book. It simplifies biochemistry beyond belief compared to this book.
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2 of 2 people found the following review helpful
5.0 out of 5 stars Excellent Book September 3, 1999
By A Customer
Format:Hardcover
This book is unmatched in it's quality for introductory biochemistry. The detailed diagrams and explainations are easy to grasp and well put together. I would strongly recommend this book for any biochemists.
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6 of 8 people found the following review helpful
5.0 out of 5 stars One of the best biochemistry book June 15, 2000
By A Customer
Format:Hardcover
I have not seen the 2000 edition yet, but the previous edition is very elegantly written. Compare with some other biochemistry text, this book provides another view into biochemistry. Almost (if not all) all the chapters have a special topic after the chapter text, showing you how we can turn the dry text into useful experimental tools for solving life's problem, scientifically. These special topics also give us a view into the physical chemistry world, which has become more and more important at the time.
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10 of 14 people found the following review helpful
5.0 out of 5 stars Excellent Book to start Biochemistry! July 9, 2001
Format:Hardcover
Mathew's Biochemistry is an excellent book to start this difficult subject! The easy diagrams and interesting notes just keeps you wanting to learn more...Read, read and read. If only it could have a more clinical focus it would be 100% perfect. Combine it with "Harper's Biochemistry" and you will soon run A+ on scores! To die for!
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1 of 1 people found the following review helpful
2.0 out of 5 stars Lots of problems with this book January 20, 2013
Format:Hardcover
I had this book for the majors'-level year long biochemistry course sequence (I was a pre-pharmacy major) at Oregon State University, where Matthews,
Van Holde, and Aherne were all teaching. Let's just say that the book chapters were only about half of what we were expected to know.
The professor who taught the first part of the sequence provided tons of his own separate notes because the book was so incomplete with regard
to enzyme kinetics and a few other topics. The professor for the second part of the sequence was actually Matthews, but he had his graduate students
lecturing most of the time, and they followed the book pretty religiously. The professor for the final part of the sequence, which covered DNA/RNA, etc did not use the book at all, and at the first class meeting, he said, "Matthews and Van Holde made a ton of errors when they wrote it, so we will not be using the book." That professor wrote and published his own lecture notes, which we used instead. The rest of the book is pretty good actually. It's pretty accessible, not too high level. Put the study time in, digest it, and you can understand it. If you have a good background in OChem and biology, and have taken a lower-level biochemistry course before taking a rigorous majors'-level course/course sequence, then you'll probably be fine. The problem sets - good luck. No solutions manual. The problems on the exams were nowhere near as easy as the ones in the book, and a number of assorted topics (like identifying the amino acids of a 9 or 10-amino acid peptide) were very weakly covered in the text but we had to know how to do that by heart for the tests. All in all, the book might be a good one to have in your library for some biochem topics, but apparently the DNA chapters should be avoided.
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Most Recent Customer Reviews
2.0 out of 5 stars cheap so i bought it
this has nothing to do with the seller; this book is AWFUL it gives problem but doesn't explain the process/thinking behind its answers, better off buying a different book
Published 7 months ago by khanh nguyen
5.0 out of 5 stars Wonderful Biochemistry book for beginners
I Am a high school student that plains on becoming a Anesthesiologist. I wanted a book that was easy to under stand and read without need of previous knowledge of chemistry or... Read more
Published 17 months ago by Raymosn
1.0 out of 5 stars Horrible Book, STAY FAR AWAY!
The 3rd edition of this book is awful. The end of chapter problems require consulting other random chapters in the book and wiki. Read more
Published on November 20, 2010 by StudentDr2B
4.0 out of 5 stars Illustrative
It's difficult to review a book on a subject as biochemistry, when you're a student, and this is the only book I've read on the subject. Read more
Published on April 3, 2000
5.0 out of 5 stars excellent text for the physical aspects of biochemistry
I have not seen the 1995 edition yet, but have the 1990 edition of Mathews and van Holde. For anyone interested in structural biology and especially protein structure, I think... Read more
Published on March 29, 1999
5.0 out of 5 stars A Definative book on the basics of Biochemistry!
A very complete source for the basics of Biochem. A must read for the budding Biochemist. Dr Mathews was my professor for this course in college and has written a very complete... Read more
Published on January 23, 1999
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