This book describes the role of the neutrophil in infection and inflammation and provides an up-to-date review of the biochemistry and physiology of this cell, highlighting the mechanisms by which they seek out and destroy pathogenic microorganisms. The development of these cells during haematopoiesis is described and the mechanisms that lead to the production of reactive oxidants and the intracellular signal transduction systems that lead to the cell's activation are reviewed. The book also discusses recent discoveries concerning the role of cytokines in the regulation of neutrophil function together with the importance of the neutrophil as a generator of inflammatory cytokines. Finally, there is a description of the biochemical defects that give rise to some of the neutrophil-associated human diseases.
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"...a useful basic reference and I would recommend it to immunologists, microbiologists, biochemists, physiologists, infectious disease specialists, hematologists, or to anyone whose interest lies in immunology or microbiology." John O. Naim, Immunological Investigations
Book Description
This book describes the role of the neutrophil in infection and inflammation and provides an up-to-date review of the biochemistry and physiology of this cell, highlighting the mechanisms by which they seek out and destroy pathogenic micro-organisms.
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First Sentence:
The neutrophil, the subject of this book, plays a key role as part of the immune response to microbial infections. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
reactive oxidant production, oxidant secretion, bloodstream neutrophils, opsonised zymosan, subcellular stores, neutrophil suspensions, oxidase molecules, subcellular pools, cytochrome molecules, myeloperoxidase deficiency, actin polymerisation, phagocytosing neutrophils, oxidase activation, primed neutrophils, reactive oxidants, myeloperoxidase system, soluble agonists, resting neutrophils, neutrophil integrins, pathogen killing, specific granules, neutrophil plasma membrane, intracellular signalling molecules, oxidase preparations, oxidase function Key Phrases - Capitalized Phrases (CAPs): (learn more)
Fluorescence Figure, New York, Cell Biol, Cell Sci New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
The neutrophil, the subject of this book, plays a key role as part of the immune response to microbial infections. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
reactive oxidant production, oxidant secretion, bloodstream neutrophils, opsonised zymosan, subcellular stores, neutrophil suspensions, oxidase molecules, subcellular pools, cytochrome molecules, myeloperoxidase deficiency, actin polymerisation, phagocytosing neutrophils, oxidase activation, primed neutrophils, reactive oxidants, myeloperoxidase system, soluble agonists, resting neutrophils, neutrophil integrins, pathogen killing, specific granules, neutrophil plasma membrane, intracellular signalling molecules, oxidase preparations, oxidase function Key Phrases - Capitalized Phrases (CAPs): (learn more)
Fluorescence Figure, New York, Cell Biol, Cell Sci New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 6
books:
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3
books
cite this book:
- The Neutrophil by Maurice B. Hallett on page 32, and page 148
- Inflammation: Basic Principles and Clinical Correlates by John I. Gallin on page 32, and page 148
- Cytokine Therapy by David W. Galvani on page 32
- Free Radicals in Biology and Medicine by Barry Halliwell on page 185
- Roitt's Essential Immunology (Essentials) by Peter Delves on page 32
See all 6 books this book cites
- Fundamentals of Surgical Practice by Andrew N. Kingsnorth on page 229
- Endothelium in Clinical Practice: Source & Target of Novel Therapies (Fundamental and Clinical Cardiology) by Gabor Rubanyi on page 192
- Adenosine Receptors: Therapeutic Aspects for Inflammatory and Immune Diseases by Gyorgy Hasko on page 96
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