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A Biologist's Guide to Analysis of DNA Microarray Data Hardcover – March 22, 2002

ISBN-13: 978-0471224907 ISBN-10: 0471224901 Edition: 1st

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Product Details

  • Hardcover: 144 pages
  • Publisher: Wiley-Liss; 1 edition (March 22, 2002)
  • Language: English
  • ISBN-10: 0471224901
  • ISBN-13: 978-0471224907
  • Product Dimensions: 0.6 x 6.3 x 9.4 inches
  • Shipping Weight: 12.6 ounces
  • Average Customer Review: 4.0 out of 5 stars  See all reviews (7 customer reviews)
  • Amazon Best Sellers Rank: #2,994,733 in Books (See Top 100 in Books)

Editorial Reviews

Review

"...a fine introduction to DNA microarray analysis using good concrete examples, well reasoned descriptions…and much-needed examination of the tools, technologies, and research resources...after reading this book, anyone new to microarray data should understand what can…be measured..." (Nature Genetics, Vol. 33, March 2003)

"...I'd recommend anyone setting out to use this methodology to buy a copy for the lab." (British Society for Cell Biology Newsletter)

"...This useful little book .... I'd recommend anyone setting out to use this methodology to buy a copy for the lab." (British Society for Developmental Biology Newsletter)

Review

"...provides a great introduction and overview of the computational methods associated with the anaylsis of microarray and chip data." - Gary Hardiman, Ph.D., Division of Biology, University of California San Diego, La Jolla, California

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Customer Reviews

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Most Helpful Customer Reviews

12 of 12 people found the following review helpful By Ronald Taylor on July 15, 2002
Format: Hardcover
This is the best short introduction that I've seen to DNA
microarray analysis - and our lab has just about every
computational biology book ever published. (We are the core
array analysis facility at the U of Colorado School of Medicine,
operating downstream of one of the largest single Affymetrix
facilities in academia.)
This book is clear, accurate, and concise - I'm very
enthusiastic about it. I've recommended it to everyone in
our lab, and to our collaborators. I have even xeroxed the
analysis flow chart in fig 2.1, annotated it a bit, and
taped it on our lab door. I found something I really liked
on just about every other page. One example: the comparison
between Euclidean and Pearson correlation distance on pp.
45-46 is the best short explanation I have ever seen.
Chapter 2 on basic data analysis is superb (it even manages
to describe the Multiple Testing problem in its limited
number of pages), and the chapters on investigating
regulatory nets and molecular classifiers give you a wonderful
taste of some cutting-edge stuff within their length constraints.
All the chapters are excellent. Biblio is very current. Price
is a little steep ... for ~150 pages, but it's a great
little book. 5 stars.
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1 of 1 people found the following review helpful By A Customer on January 22, 2004
Format: Hardcover
True to its stated purpose: best used as a roadmap by mathematically unsophisticated newcomers to analysis of microarray data. Somewhat superficial, and it becomes more so in later chapters. Does not explore harder issues in detail. Does not touch upon future directions of the technology. Its advocacy of the Unix awk program is anachronistic; tellingly, the reference cited for awk is from 1988. Not a groundbreaking book, just solid practical advice.
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1 of 2 people found the following review helpful By A Customer on May 11, 2003
Format: Hardcover
If you just want an general idea of how the microarray and analysis works so you can understand other people's data and method. And you willing to pay 40 bucks for 125 pages(including index) instead of search free resources online. This will be the book for you.
If you want to do array analysis your self. try other books.
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6 of 10 people found the following review helpful By A Customer on October 14, 2002
Format: Hardcover
"This book is really not worth your money--it is a very simplistic and not up-to-date treatment of DNA microarrays. The field is progressing fast and, with less than 150 pages, this early book is already obsolete. Presentation of statistical methods is quite weak."
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