This book attempts to explain the mechanisms by which surfactants - specifically, the surface-active phospholipids - exert their physiological functions in the body. There is much controversy as to the role of surfactant in the lung, and the veracity of the various alveolar models, which are clearly evaluated in The Biology of Surfactant. The text goes on to describe the nature of surfactant in the gastro-intestinal tract, joints and at tissue surfaces in other organs where it could have several useful functions. These are related to work on synthetic- surfactants which may shed light on natural mechanisms with important implications for medical research. In each of these the underlying physico-chemical principles are emphasized in a manner accessible to the biologist and physician. By giving an overview of theories as to the role and mechanism of surfactants - including hid own forthright views - Professor Hills has provided a comprehensive and stimulating text. The volume will appeal to researchers and students of physiology, paediatrics, obstetrics, rheurnatology, neonatology; specialists in pulmonary physiology and chest diseases; surgeons, biochemists, microbiologists whose work relates to surfactants in the lung and other organs.
