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Biomedical Chemistry: Applying Chemical Principles to the Understanding and Treatment of Disease
 
 
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Biomedical Chemistry: Applying Chemical Principles to the Understanding and Treatment of Disease [Hardcover]

Paul F. Torrence (Editor)

Price: $148.00 & this item ships for FREE with Super Saver Shipping. Details
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Book Description

January 24, 2000
How basic chemical ideas help advance the understanding and treatment of disease Biomedical Chemistry presents clear, concise coverage of the application of chemistry to drug discovery and determination of disease etiology, highlighting its role in the explosive growth of biotechnology and molecular biology. Through expert contributions from leading researchers in diverse fields, the book provides readers with an understanding of how fundamental chemical concepts are used in the development of novel approaches to the major problems in medicine today. The authors explain both the science and reasoning underlying each experimental approach, exploring cutting-edge developments in AIDS, cancer, alcoholism, Parkinson's disease, trypanosomiasis, emphysema, and malaria. Contemporary research problems discussed include:
* Mechanism-based drug discovery
* Design of new antitumor and antiviral agents
* Targeting tumors using magnetic drug delivery
* Antisense and antigene agents
Easily accessible to anyone with a solid undergraduate background in chemistry, Biomedical Chemistry is an excellent resource for researchers in health-related fields as well as anyone seeking an overview of frontier topics in medicinal chemistry, organic chemistry, and biochemistry.

Editorial Reviews

Review

"Explains the application of chemistry to drug discovery and determination of disease etiology...provides an understanding of how fundamental chemical concepts are used..." (SciTech Book News, March 2001)

"At what must be considered a modest price, this book is warmly recommended as a good overall survey of the field to chemists and biochemists working in biomedical or related areas. It will also appeal to teachers of organic chemistry as a source book of medically relevant example..." (Journal of the American Chemical Society, Vol. 123, No. 30, 2001)

"In an age of disposable artifacts and useless gadgets, this is a book to pick up frequently, read slowly, assimilate, and above all enjoy." (Pharmaceutical Research, Vol. 18, No. 9, September 2001)

"A fascinating book...one of the best summaries of the new approach that I have seen." (Chemistry & Industry, 19 November, 2001)

"...an essential handbook..." (Journal of Natural Products, 2003)

From the Back Cover

How basic chemical ideas help advance the understanding and treatment of disease Biomedical Chemistry presents clear, concise coverage of the application of chemistry to drug discovery and determination of disease etiology, highlighting its role in the explosive growth of biotechnology and molecular biology. Through expert contributions from leading researchers in diverse fields, the book provides readers with an understanding of how fundamental chemical concepts are used in the development of novel approaches to the major problems in medicine today. The authors explain both the science and reasoning underlying each experimental approach, exploring cutting-edge developments in AIDS, cancer, alcoholism, Parkinson's disease, trypanosomiasis, emphysema, and malaria. Contemporary research problems discussed include:
* Mechanism-based drug discovery
* Design of new antitumor and antiviral agents
* Targeting tumors using magnetic drug delivery
* Antisense and antigene agents
Easily accessible to anyone with a solid undergraduate background in chemistry, Biomedical Chemistry is an excellent resource for researchers in health-related fields as well as anyone seeking an overview of frontier topics in medicinal chemistry, organic chemistry, and biochemistry.

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Inside This Book (learn more)
First Sentence:
During the past 20 years ( at the time of writing), remarkable advances have been made toward understanding the cellular roles of the natural polyamines spermidine and spermine. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
thioureylene compounds, trioxane alcohol, ribozyme mimics, magnetic drug delivery, fluorinated catecholamines, natural artemisinin, mononucleotide prodrugs, aziridinium ion formation, impairment subsides, bond hydrolysis reactions, growing melanin, terminal pyruvate, imido analogs, phosphotriester derivatives, nitrosyl cyanide, cationic particles, vindoline moiety, energy impairment, hydrolase inhibitors, melanin pathway, melanoma melanin, supporting electrode, biomedical chemistry, spermine synthase, antisense reagents
Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Cancer Res, Tetrahedron Lett, John Wiley, Applying Chemical Principles, Biomedical Chemistry, American Chemical Society, Brain Res, Academic Press, Nucleic Acids Res, Oxford Univ, Nucleosides Nucleotides, Neural Transm, Antiviral Res, United States, Drug Deliv, National Institutes of Health, Plenum Press, Cell Biol, Eli Lilly, Life Sci, Symposium Series, Drug Metab, Melanoma Res, The Pigmentary System
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