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Bioprocess Engineering: Basic Concepts (2nd Edition)
 
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Bioprocess Engineering: Basic Concepts (2nd Edition) [Hardcover]

Michael L. Shuler (Author), Fikret Kargi (Author)
4.0 out of 5 stars  See all reviews (12 customer reviews)

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Book Description

0130819085 978-0130819086 November 10, 2001 2
Bioprocess Engineering, Second Edition thoroughly updates the leading introductory textbook on biochemical and bioprocess engineering to reflect advances that are transforming the field -- from genomics to cellular engineering, modeling to nonconventional biological systems. It introduces techniques with wide applicability in pharmaceuticals, biologics, medicine, environmental engineering, and beyond.

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Editorial Reviews

From the Publisher

An introduction to the fundamentals of cellular structure and physiology, protein structure and function, genetics, and molecular biology -- for those with an understanding of the principles of process engineering, but with a limited background in biology. --This text refers to an alternate Hardcover edition.

From the Back Cover

The complete, fully updated introduction to biochemical and bioprocess engineering.

Bioprocess Engineering, Second Edition is a comprehensive update of the world's leading introductory textbook on biochemical and bioprocess engineering. Drs. Michael L. Shuler and Fikret Kargi review the relevant fundamentals of biochemistry, microbiology, and molecular biology, introducing key principles that enable bioprocess engineers to achieve consistent control over biological activity. This edition reflects powerful advances that are transforming the field, ranging from genetic sequencing to new techniques for producing proteins from recombinant DNA. It introduces techniques with broad application to the production of pharmaceuticals, biologics, and commodities; to medical applications such as tissue engineering and gene therapy; and for solving critical environmental problems. This new edition includes:

  • Essential biological basics: microorganism structure and functions, major metabolic pathways, enzymes, microbial genetics, kinetics, and stoichiometry of growth
  • New coverage of posttranslational processing of proteins-an essential technique for manufacturing therapeutic proteins
  • In-depth coverage of animal cell culture processes
  • New coverage of noncarbohydrate metabolism
  • Functional genomics and cellular engineering: concepts, techniques, and applications
  • Applying bioprocess engineering approaches to biomedical applications
  • Nonconventional biological systems applications, including host-vector systems for producing proteins from recombinant DNA
  • Extensive coverage of mixed cultures, including advanced wastewater treatment processes
  • Expanded coverage of modeling, including models in continuous cultures and cybernetic modeling
  • How the rapidly evolving governmental regulatory environment constrains bioprocess design and modification

Bioprocess Engineering, Second Edition makes extensive use of illustrations, examples, and problems, and contains extensive references for further reading as well as a detailed appendix describing traditional bioprocesses.


Product Details

  • Hardcover: 576 pages
  • Publisher: Prentice Hall; 2 edition (November 10, 2001)
  • Language: English
  • ISBN-10: 0130819085
  • ISBN-13: 978-0130819086
  • Product Dimensions: 9.4 x 6.9 x 1.3 inches
  • Shipping Weight: 2.1 pounds (View shipping rates and policies)
  • Average Customer Review: 4.0 out of 5 stars  See all reviews (12 customer reviews)
  • Amazon Best Sellers Rank: #166,676 in Books (See Top 100 in Books)

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Customer Reviews

12 Reviews
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Average Customer Review
4.0 out of 5 stars (12 customer reviews)
 
 
 
 
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Most Helpful Customer Reviews

16 of 17 people found the following review helpful:
5.0 out of 5 stars An excellent guide for the student or professional., February 13, 2000
By 
Brian Gierl (West Point, PA) - See all my reviews
Bioprocess Engineering is an excellent reference for anyone interested in biotechnology. It begins by introducing the cell, enzymes and major metabolic pathways and then moves into an analysis of growth kinetics and stoichiometry for both wild type and genetically engineered cells. Then the theme turns to the design of bioreactors and the basics of product recovery and purification.

Overall, the book provides an excellent overview of bioprocess engineering. The text is simple to read and is based upon the basic systems that would be encountered in the real world. The examples demonstrate how to solve problems via multiple approaches and the graphs provide an excellent reference. More advanced sections lay out problem solving techniques for more challenging systems.

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7 of 8 people found the following review helpful:
3.0 out of 5 stars Good, but has glaring flaws, May 7, 2003
By 
Patrick (Auburn, AL United States) - See all my reviews
This review is from: Bioprocess Engineering: Basic Concepts (2nd Edition) (Hardcover)
This was the book for my introductory bioprocess engineering course. I felt it covered the quantitative areas, such as enzyme kinetics, bioreactor design, stoichiometry, etc.., quite well. However, the qualitative sections, such as DNA replication, metabolic pathways, and cell function, etc.., are explained way too quickly and lightly for someone with little or no training in Biology. Upon reading a few pages into one of these qualitative sections, you quickly find the author throwing terms at you that he never defined (to be fair, it would take an extra 100 pages to define all of these terms). Also, the text has some really unfortunate typos, typos so severe they may actually hinder your learning (subscripts change for no reason, two different constants given the same symbol, etc.) Biology folks will be happy, but ChEs with no knowledge of Biology may want to stick to the section on bioprocess engineering in Fogler.
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3 of 3 people found the following review helpful:
2.0 out of 5 stars Competent text, but beware of a few downsides, April 21, 2009
This review is from: Bioprocess Engineering: Basic Concepts (2nd Edition) (Hardcover)
Even though the textbook's content is well written and clear, there were several big downsides (for me).

The first was that the text sometimes skips steps in the derivations, and simply presents the final solutions. This is fine if you simply want the end result. But, if you are interested in the fundamentals as well, you will be slightly disappointed.

The second major drawback for me was the abysmal quality of the illustrations. All the illustrations are in black and white, and they are beyond plain. They appear to have been done in Microsoft Paint by someone with little passion for their work.

For someone who is a visual learner, the illustrations might be a deal breaker when it comes to this text.

Aside from that, the content is quite competently written.
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