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Bioprocess Engineering Principles
 
 
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Bioprocess Engineering Principles [Paperback]

Pauline M. Doran (Author)
4.2 out of 5 stars  See all reviews (5 customer reviews)

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Book Description

0122208560 978-0122208560 May 25, 1995 1
The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture, and environmental management. Scientific breakthroughs in gene expression, protein engineering, and cell fusion are being translated by a strengthening biotechnology industry into revolutionary new products and services. Many a student has been enticed by the promise of biotechnology and the excitement of being near the cutting edge of scientific advancement. However, graduates trained in molecular biology and cell manipulation soon realize that these techniques are only part of the picture. Reaping the full benefits of biotechnology requires manufacturing capability involving the large-scale processing of biological material. Increasingly, biotechnologists are being employed by companies to work in cooperation with chemical engineers to achieve pragmatic commercial goals. For many years, aspects of biochemistry and molecular genetics have been included in chemical engineering curricula, yet there has been little attempt until recently to teach aspects of engineering applicable to process design to biotechnologists.
This textbook is the first to present the principles of bioprocess engineering in a way that is accessible to biological scientists. Other texts on bioprocess engineering currently available assume that the reader already has engineering training. On the other hand, chemical engineering textbooks do not consider examples from bioprocessing, and are written almost exclusively with the petroleum and chemical industries in mind. This publication explains process analysis from an engineering point of view, but refers exclusively to the treatment of biological systems. Over 170 problems and worked examples encompass a wide range of applications, including recombinant plant and animal cell cultures, immobilized catalysts, as well as traditional fermentation systems.

Key Features
* First book to present the principles of bioprocess engineering in a way that is accessible to biological scientists
* Explains process analysis from an engineering point of view, but uses worked examples relating to biological systems
* Comprehensive, single-authored
* 170 problems and worked examples encompass a wide range of applications, involving recombinant plant and animal cell cultures, immobilized catalysts, and traditional fermentation systems
* 13 chapters, organized according to engineering sub-disciplines, are grouped in four sections--Introduction, Material and Energy Balances, Physical Processes, and Reactions and Reactors
* Each chapter includes a set of problems and exercises for the student, key references, and a list of suggestions for further reading
* Includes useful appendices, detailing conversion factors, physical and chemical property data, steam tables, mathematical rules, and a list of symbols used
* Suitable for course adoption--follows closely curricula used on most bioprocessing and process biotechnology courses at senior undergraduate and graduate levels

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Editorial Reviews

Review

From the Prepublication Reviews:
"In general the text is very well written, well organized and is of high quality in all respects.... The emphasis on physical explanations that accompany the equations is very helpful.... The coverage is very complete and comprehensive."
-DAVID DIBIASIO, WORCESTER POLYTECHNIC INSTITUTE, MASSACHUSETTS, USA

From the Back Cover

The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture, and environmental management. Scientific breakthroughs in gene expression, protein engineering, and cell fusion are being translated by a strengthening biotechnology industry into revolutionary new products and services. Many a student has been enticed by the promise of biotechnology and the excitement of being near the cutting edge of scientific advancement. However, graduates trained in molecular biology and cell manipulation soon realise that these techniques are only part of the picture. Reaping the full benefits of biotechnology requires manufacturing capability involving the large-scale processing of biological material. Increasingly, biotechnologists are being employed by companies to work in cooperation with chemical engineers to achieve pragmatic commercial goals. For many years, aspects of biochemistry and molecular genetics have been included in chemical engineering curricula, yet there has been little attempt until recently to teach aspects of engineering applicable to process design to biotechnologists.
This textbook is the first to present the principles of bioprocess engineering in a way that is accessible to biological scientists. Other texts on bioprocess engineering currently available assume that the reader already has engineering training. On the other hand, chemical engineering textbooks do not consider examples from bioprocessing, and are written almost exclusively with the petroleum and chemical industries in mind. This publication explains process analysis from an engineering point of view, but refers exclusively to the treatment of biological systems. Over 170 problems and worked examples encompass a wide range of applications, including recombinant plant and animal cell cultures, immobilised catalysts, as well as traditional fermentation systems.

Product Details

  • Paperback: 439 pages
  • Publisher: Academic Press; 1 edition (May 25, 1995)
  • Language: English
  • ISBN-10: 0122208560
  • ISBN-13: 978-0122208560
  • Product Dimensions: 9.9 x 7.6 x 1 inches
  • Shipping Weight: 2.1 pounds (View shipping rates and policies)
  • Average Customer Review: 4.2 out of 5 stars  See all reviews (5 customer reviews)
  • Amazon Best Sellers Rank: #100,894 in Books (See Top 100 in Books)

 

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Average Customer Review
4.2 out of 5 stars (5 customer reviews)
 
 
 
 
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3 of 3 people found the following review helpful:
5.0 out of 5 stars "Biochemical Engineering" for biology students, October 17, 2005
This review is from: Bioprocess Engineering Principles (Paperback)
This is a comprehensive textbook on biochemical engineering suitable for students with only elementary knowledge of mathematics and engineering. It covers all the main aspects of the field but with minimal prerequisite knowledge of differential calculus and statistics. In the first part are given concepts of mass and energy balances, thermodynamics, hydrodynamics, heat and mass transfer, and unit operations. It is followed with reaction principles, kinetics of biological processes, heterogeneous reactions, and reactor engineering principles. Each topic includes practical examples and numerical solutions to problems. Students with biological background will find this book as the most appropriate introduction to biotechnology.
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2 of 2 people found the following review helpful:
3.0 out of 5 stars One of a better book, March 20, 2000
By A Customer
This review is from: Bioprocess Engineering Principles (Paperback)
This is one of a better intro textbook for people interested in Bioprocess Engineering. It covers a lot of engineering fundamentals such as Fluid Mechanics, Heat Transfer, etc. However, it is lack of biology concept (which is needed to give better presentation of the materials). Problems given at the end of chapter will be more useful when accompanied with numerical answers.
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5.0 out of 5 stars Excellent book, November 24, 2009
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This review is from: Bioprocess Engineering Principles (Paperback)
The book is really complete. It doesn't assume you have extensive prior knowledge. Well organized, with nice in book exercises. Very recommendable.
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Inside This Book (learn more)
First Sentence:
The interdisciplinary nature of bioprocessing is evident if we look at the stages of development required for a complete industrial process. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
total effectiveness factor, gmol glucose, shell mass balance, batch culture time, true biomass yield, observed biomass yield, inoculum tank, internal effectiveness factor, batch sterilisation, continuous sterilisers, true kinetic parameters, batch reaction time, fermentation slurry, minimum stirrer speed, unity bracket, external effectiveness factor, immobilised cells, mycelial broths, many bioprocesses, stirred fermenter, maximum cell concentration, sterilisation temperature, substrate concentration profile, fermentation monitoring, adsorption operations
Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Pergamon Press, Academic Press, Comprehensive Biotechnology, Marcel Dekker, International Critical Tables, Blackwell Scientific, Basic Bioreactor Design, Ellis Horwood, Elsevier Applied Science, Houghton Mifflin, Oxford University Press, Total Feed, Basic Biotechnology, Gum Cells, Permeable Catalysts, Peter Peregrinus
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