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Biostatistics in Clinical Trials (Wiley Reference Series in Biostatistics) [Hardcover]

Carol K. Redmond (Editor), Theodore Colton (Editor)

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Book Description

May 3, 2001 0471822116 978-0471822110 1
The second volume in the Wiley reference series in Biostatistics.
Featuring articles from the prestigious Encyclopedia of Biostatistics, many of which have been fully revised and updated to include recent developments, Biostatistics in Clinical Trials also includes up to 25% newly commissioned material reflecting the latest thinking in:
  • Bayesian methods
  • Benefit/risk assessment
  • Cost-effectiveness
  • Ethics
  • Fraud

With exceptional contributions from leading experts in academia, government and industry, Biostatistics in Clinical Trials has been designed to complement existing texts by providing extensive, up-to-date coverage and introducing the reader to the research literature.
Offering comprehensive coverage of all aspects of clinical trials Biostatistics in Clinical Trials:

  • Includes concise definitions and introductions to numerous concepts found in current literature
  • Discusses the software and textbooks available
  • Uses extensive cross-references helping to facilitate further research and enabling the reader to locate definitions and related concepts

Biostatistics in Clinical Trials offers both academics and practitioners from various disciplines and settings, such as universities, the pharmaceutical industry and clinical research organisations, up-to-date information as well as references to assist professionals involved in the design and conduct of clinical trials.


Editorial Reviews

Review

"Every professional statistician should have this well written and well composed book in his/her collection." (Journal of Statistical Computation and Simulation, September 2005)

"...strongly recommended as a reference for an overview of biostatistics in clinical trials..." (Statistical Methods in Medical Research, Vol.12, No.4, 2003)

"highly informative and useful book" (Journal of Tropical Paediatrics, February 2002)

"This highly informative and readable book is part of the Wiley Reference Series in Biostatistics. This book will be a useful tool for generating the required evidence and is a handy reference for the design, conduct, analysis and interpretation of clinical trials." (Journal of Tropical Pediatricstrics)

"...a valuable reference and an excellent resource to add to classroom and other teaching tools..." (Oncology, Vol.63, No.1, 2002) 

From the Back Cover

The second volume in the Wiley reference series in Biostatistics.

Featuring articles from the prestigious Encyclopedia of Biostatistics, many of which have been fully revised and updated to include recent developments, Biostatistics in Clinical Trials also includes up to 25% newly commissioned material reflecting the latest thinking in:
* Bayesian methods

* Benefit/risk assessment

* Cost-effectiveness

* Ethics

* Fraud
With exceptional contributions from leading experts in academia, government and industry, Biostatistics in Clinical Trials has been designed to complement existing texts by providing extensive, up-to-date coverage and introducing the reader to the research literature.

Offering comprehensive coverage of all aspects of clinical trials Biostatistics in Clinical Trials:
* Includes concise definitions and introductions to numerous concepts found in current literature

* Discusses the software and textbooks available

* Uses extensive cross-references helping to facilitate further research and enabling the reader to locate definitions and related concepts
Biostatistics in Clinical Trials offers both academics and practitioners from various disciplines and settings, such as universities, the pharmaceutical industry and clinical research organisations, up-to-date information as well as references to assist professionals involved in the design and conduct of clinical trials.

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Inside This Book (learn more)
First Sentence:
The simplest design of a randomized clinical trial is to enter a predetermined number of patients (i.e. use a fixed sample size) and to assign treatment by randomization with equal probability for each patient. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
comparable case sets, parallel treatment designs, study biostatistician, cluster randomization trials, clinical research pharmacist, full analysis set, similarity trial, heart disease trials, randomized treatment assignment, cooperative group program, group sequential tests, group sequential methods, clinical tnals, stochastic curtailment, curtailed tests, streptomycin trial, study chairperson, clinical teals, several experimental treatments, basic estimators, logrank statistic, screening stops, cancer screening trials, statistical reviewers, group sequential designs
Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, New England Journal of Medicine, Journal of the American Medical Association, British Medical Journal, Oxford University Press, Coronary Drug Project, Journal of the American Statistical Association, Journal of Chronic Diseases, Journal of the Royal Statistical Society, National Institutes of Health, Marcel Dekker, National Heart, American Journal of Epidemiology, Journal of Clinical Oncology, Cochrane Collaboration, Compliance Assessment, American Journal of Public Health, Bradford Hill, Journal of Clinical Epidemiology, University Group Diabetes Program, Applied Statistics, Blood Institute, Declaration of Helsinki, American Statistician, Annals of Internal Medicine
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